methyl 6-[3-(4-hydroxyphenyl)-5-phenyl-1H-pyrrole-2-carboxamido] hexanoate

Base Information

• Chemical Name: methyl 6-[3-(4-hydroxyphenyl)-5-phenyl-1H-pyrrole-2-carboxamido] hexanoate
• CAS No.: 1402160-15-9
• Molecular Formula: C₂₄H₂₆N₂O₄
• Molecular Weight: 406.481
• Mol file: 1402160-15-9.mol

Synonyms:methyl 6-[3-(4-hydroxyphenyl)-5-phenyl-1H-pyrrole-2-carboxamido] hexanoate

Chemical Property of methyl 6-[3-(4-hydroxyphenyl)-5-phenyl-1H-pyrrole-2-carboxamido] hexanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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Technology Process of methyl 6-[3-(4-hydroxyphenyl)-5-phenyl-1H-pyrrole-2-carboxamido] hexanoate

There total 17 articles about methyl 6-[3-(4-hydroxyphenyl)-5-phenyl-1H-pyrrole-2-carboxamido] hexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

methyl 6-[3-(4-benzyloxyphenyl)-5-phenyl-1H-pyrrole-2-carboxamido] hexanoate (1402160-20-6) → methyl 6-[3-(4-hydroxyphenyl)-5-phenyl-1H-pyrrole-2-carboxamido] hexanoate (1402160-15-9)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In methanol; at 20 ℃; for 12h;

Reference yield: 46.0%

methyl 6-[3-(4-methoxyphenyl)-5-phenyl-1H-pyrrole-2-carboxamido] hexanoate (1402160-16-0) → methyl 6-[3-(4-hydroxyphenyl)-5-phenyl-1H-pyrrole-2-carboxamido] hexanoate (1402160-15-9)

Guidance literature:

methyl 6-[3-(4-methoxyphenyl)-5-phenyl-1H-pyrrole-2-carboxamido] hexanoate; With boron tribromide; In dichloromethane; at 0 - 20 ℃; for 16h; Inert atmosphere;

With methanol; In dichloromethane; at 0 ℃;

Reference yield: 46.0%

methanol (67-56-1) + methyl 6-[3-(4-methoxyphenyl)-5-phenyl-1H-pyrrole-2-carboxamido] hexanoate → methyl 6-[3-(4-hydroxyphenyl)-5-phenyl-1H-pyrrole-2-carboxamido] hexanoate (1402160-15-9)

Guidance literature:

methyl 6-[3-(4-methoxyphenyl)-5-phenyl-1H-pyrrole-2-carboxamido] hexanoate; With boron tribromide; In dichloromethane; at 0 - 20 ℃; for 16h; Inert atmosphere;

methanol; In dichloromethane; at 0 ℃;

upstream raw materials:

methyl 6-[3-(4-methoxyphenyl)-5-phenyl-1H-pyrrole-2-carboxamido] hexanoate

methyl 6-[3-(4-benzyloxyphenyl)-5-phenyl-1H-pyrrole-2-carboxamido] hexanoate

(E)-1-methoxy-4-(2-nitrovinyl)benzene

(E)-3-(4-hydroxyphenyl)-1-phenyl-2-propen-1-one

Downstream raw materials:

N-(6-(hydroxyamino)-6-oxohexyl)-3-(4-hydroxyphenyl)-5-phenyl-1H-pyrrole-2-carboxamide