Cyano-(1-cyano-4,4-dipropyl-cyclohexyl)-acetic acid ethyl ester

Base Information

• Chemical Name: Cyano-(1-cyano-4,4-dipropyl-cyclohexyl)-acetic acid ethyl ester
• CAS No.: 948552-26-9
• Molecular Formula: C₁₈H₂₈N₂O₂
• Molecular Weight: 304.433
• Mol file: 948552-26-9.mol

Synonyms:Cyano-(1-cyano-4,4-dipropyl-cyclohexyl)-acetic acid ethyl ester

Chemical Property of Cyano-(1-cyano-4,4-dipropyl-cyclohexyl)-acetic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cyano-(1-cyano-4,4-dipropyl-cyclohexyl)-acetic acid ethyl ester

There total 3 articles about Cyano-(1-cyano-4,4-dipropyl-cyclohexyl)-acetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4,4-dipropylcyclohex-2-en-1-one (60729-41-1) → Cyano-(1-cyano-4,4-dipropyl-cyclohexyl)-acetic acid ethyl ester (948552-26-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 98 percent / H₂ / 10percent Pd/C / ethyl acetate / 5 h / 2585.7 Torr / Ambient temperature

2: 89 percent / ammonium acetate, acetic acid / toluene / Heating

3: ethanol; H₂O / 5 h / Heating

With ammonium acetate; hydrogen; acetic acid; palladium on activated charcoal; In ethanol; water; ethyl acetate; toluene;

DOI:10.1021/jm00173a010

Reference yield:

4,4-di-n-propylcyclohexanone (123018-62-2) → Cyano-(1-cyano-4,4-dipropyl-cyclohexyl)-acetic acid ethyl ester (948552-26-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / ammonium acetate, acetic acid / toluene / Heating

2: ethanol; H₂O / 5 h / Heating

With ammonium acetate; acetic acid; In ethanol; water; toluene;

DOI:10.1021/jm00173a010

Reference yield:

potassium cyanide (151-50-8) + ethyl α-cyano-α-(4,4-dipropylcyclohexylidene)acetate (130065-93-9) → Cyano-(1-cyano-4,4-dipropyl-cyclohexyl)-acetic acid ethyl ester (948552-26-9)

Guidance literature:

In ethanol; water; for 5h; Heating;

DOI:10.1021/jm00173a010

upstream raw materials:

potassium cyanide

ethyl α-cyano-α-(4,4-dipropylcyclohexylidene)acetate

4,4-dipropylcyclohex-2-en-1-one

4,4-di-n-propylcyclohexanone

Downstream raw materials:

4,4-dipropyl-1-carboxycyclohexane-1-acetic acid

4,4-dipropyl-1-carboxycyclohexane-1-acetic acid anhydride

N,N-dimethyl-8,8-dipropyl-2-azaspiro [4,5] decane-2-propanamine dihydrochloride

atiprimod