Benzyl 4-(methylamino)piperidine-1-carboxylate

Base Information

Chemical Name:Benzyl 4-(methylamino)piperidine-1-carboxylate
CAS No.:405057-75-2
Molecular Formula:C14H20 N2 O2
Molecular Weight:248.325
Hs Code.:2933399090
DSSTox Substance ID:DTXSID50595198
Wikidata:Q82490158
Mol file:405057-75-2.mol

Synonyms:405057-75-2;1-Cbz-4-Methylaminopieridine;benzyl 4-(methylamino)piperidine-1-carboxylate;1-Cbz-4-methylaminopiperidine;4-METHYLAMINO-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER;1-Piperidinecarboxylic acid, 4-(methylamino)-, phenylmethyl ester;MFCD07772081;1-Cbz-4-(methylamino)piperidine;Benzyl 4-(methylamino)-1-piperidinecarboxylate;SCHEMBL1780742;AMY4834;DTXSID50595198;UKMMXAXGJCWGTF-UHFFFAOYSA-N;AB6234;AKOS005258713;SB11677;DS-13108;SY247932;DB-070024;CS-0069684;1-(Benzyloxycarbonyl)-4-methylaminopiperidine;benzyl4-(methylamino)piperidine-1-carboxylate;EN300-7126899;A825143;1-Piperidinecarboxylicacid,4-(methylamino)-,phenylmethylester

Suppliers and Price of Benzyl 4-(methylamino)piperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Benzyl4-(Methylamino)piperidine-1-carboxylate
100mg
$ 45.00

TRC
Benzyl4-(Methylamino)piperidine-1-carboxylate
500mg
$ 125.00

Chemenu
1-Cbz-4-Methylaminopieridine 95%
25g
$ 656.00

Chemenu
1-Cbz-4-Methylaminopieridine 95%
10g
$ 350.00

Chemenu
1-Cbz-4-Methylaminopieridine 95%
5g
$ 219.00

American Custom Chemicals Corporation
4-METHYLAMINO-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER 95.00%
5G
$ 4966.50

Ambeed
1-Cbz-4-Methylaminopieridine 97%
1g
$ 62.00

Ambeed
1-Cbz-4-Methylaminopieridine 97%
250mg
$ 29.00

Ambeed
1-Cbz-4-Methylaminopieridine 97%
100mg
$ 20.00

Ambeed
1-Cbz-4-Methylaminopieridine 97%
10g
$ 334.00

Total 21 raw suppliers

Chemical Property of Benzyl 4-(methylamino)piperidine-1-carboxylate

Chemical Property:

PSA：41.57000
LogP:2.33580
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:248.152477885
Heavy Atom Count:18
Complexity:257

Purity/Quality:

97% ^*data from raw suppliers

Benzyl4-(Methylamino)piperidine-1-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNC1CCN(CC1)C(=O)OCC2=CC=CC=C2

Technology Process of Benzyl 4-(methylamino)piperidine-1-carboxylate

There total 2 articles about Benzyl 4-(methylamino)piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 19099-93-5
benzyl 4-oxo-1-piperidinecarboxylate

: 593-51-1
methylamine hydrochloride

: 405057-75-2
4-methylamino-piperidine-1-carboxylic acid benzyl ester

Guidance literature:: benzyl 4-oxo-1-piperidinecarboxylate; methylamine hydrochloride; With sodium tris(acetoxy)borohydride; acetic acid; In 1,2-dichloro-ethane; at 20 ℃;

With sodium hydrogencarbonate; In water; 1,2-dichloro-ethane;

Reference yield:

: 19099-93-5
benzyl 4-oxo-1-piperidinecarboxylate

: 74-89-5
methylamine

: 405057-75-2
4-methylamino-piperidine-1-carboxylic acid benzyl ester

Guidance literature:: benzyl 4-oxo-1-piperidinecarboxylate; methylamine; In 1,4-dioxane; ethanol; at 20 ℃; for 0.25h;

With sodium tris(acetoxy)borohydride; In 1,4-dioxane; ethanol; at 20 ℃; for 15h;

Reference yield: 68.0%

: 1174020-25-7,2064219-13-0
(2S,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxylic acid

: 405057-75-2
4-methylamino-piperidine-1-carboxylic acid benzyl ester

: 1552307-00-2
C₂₈H₃₄N₄O₅

Guidance literature:: With 2-chloro-1-methyl-pyridinium iodide; triethylamine; In dichloromethane; at 50 ℃; for 1h;
DOI:10.1016/j.bmcl.2013.12.101