tert-butyl 3-(2-chloro-4-(methoxycarbonyl)benzylidene)azetidine-1-carboxylate

Base Information

Chemical Name:tert-butyl 3-(2-chloro-4-(methoxycarbonyl)benzylidene)azetidine-1-carboxylate
CAS No.:1396722-97-6
Molecular Formula:C₁₇H₂₀ClNO₄
Molecular Weight:337.803
Hs Code.:

Synonyms:tert-butyl 3-(2-chloro-4-(methoxycarbonyl)benzylidene)azetidine-1-carboxylate

Suppliers and Price of tert-butyl 3-(2-chloro-4-(methoxycarbonyl)benzylidene)azetidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of tert-butyl 3-(2-chloro-4-(methoxycarbonyl)benzylidene)azetidine-1-carboxylate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of tert-butyl 3-(2-chloro-4-(methoxycarbonyl)benzylidene)azetidine-1-carboxylate

There total 3 articles about tert-butyl 3-(2-chloro-4-(methoxycarbonyl)benzylidene)azetidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 398489-26-4
tert-butyl 3-oxoazetidine-1-carboxylate

: (2-chloro-4-(methoxycarbonyl)benzyl)triphenylphosphonium bromide

: 1396722-97-6
tert-butyl 3-(2-chloro-4-(methoxycarbonyl)benzylidene)azetidine-1-carboxylate

Guidance literature:: (2-chloro-4-(methoxycarbonyl)benzyl)triphenylphosphonium bromide; With sodium hydride; In paraffin oill; N,N-dimethyl-formamide; at 0 ℃; for 0.25h;

tert-butyl 3-oxoazetidine-1-carboxylate; In N,N-dimethyl-formamide; paraffin oil; at 65 ℃;

Reference yield:

: 56525-63-4
methyl 3-chloro-4-methyl-benzoate

: 1396722-97-6
tert-butyl 3-(2-chloro-4-(methoxycarbonyl)benzylidene)azetidine-1-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: N-Bromosuccinimide / dibenzoyl peroxide / tetrachloromethane / 6 h / Reflux

2.1: toluene / 6 h / 70 °C

3.1: sodium hydride / N,N-dimethyl-formamide; paraffin oill / 0.25 h / 0 °C

3.2: 65 °C

With N-Bromosuccinimide; sodium hydride; dibenzoyl peroxide; In tetrachloromethane; paraffin oill; N,N-dimethyl-formamide; toluene;

Reference yield:

: 74733-30-5
methyl 4-Bromomethyl-3-chlorobenzoate

: 1396722-97-6
tert-butyl 3-(2-chloro-4-(methoxycarbonyl)benzylidene)azetidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: toluene / 6 h / 70 °C

2.1: sodium hydride / N,N-dimethyl-formamide; paraffin oill / 0.25 h / 0 °C

2.2: 65 °C

With sodium hydride; In paraffin oill; N,N-dimethyl-formamide; toluene;