C₆₂H₇₁NO₁₇

Base Information

• Chemical Name: C₆₂H₇₁NO₁₇
• CAS No.: 849342-14-9
• Molecular Formula: C₆₂H₇₁NO₁₇
• Molecular Weight: 1102.24
• Mol file: 849342-14-9.mol

Synonyms:C₆₂H₇₁NO₁₇

Chemical Property of C₆₂H₇₁NO₁₇

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₆₂H₇₁NO₁₇

There total 17 articles about C₆₂H₇₁NO₁₇ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

7,9-anisaldehyde acetal-9-desoxo-10-epi-baccatin III (849213-10-1) → C62H71NO17 (849342-14-9)

Guidance literature:

With dicyclohexyl-carbodiimide; In dichloromethane; toluene; at 20 ℃; for 23h;

Reference yield:

iso-butyl sidechain acid (849213-13-4) + 7,9-anisaldehyde acetal-9-desoxo-10-epi-baccatin III (849213-10-1) → C62H71NO17 (849342-14-9)

Guidance literature:

With 4-pyrrolidin-1-ylpyridine; dicyclohexyl-carbodiimide; In toluene; at 20 ℃; for 23h;

Reference yield:

taxol (33069-62-4) → C62H71NO17 (849342-14-9)

Guidance literature:

Multi-step reaction with 10 steps

1: 1H-imidazole / N,N-dimethyl-formamide / 20 h / 20 °C

2: water; hydrazine / Isopropyl acetate / 1 h / 20 °C

3: dmap / dichloromethane / 3 h / 20 °C

4: tetra-n-propylammonium perruthenate.; 4-methylmorpholine N-oxide / dichloromethane / 22 h / 20 °C

5: sodium tetrahydroborate / methanol; ethanol / 5 h / 0 °C

6: dmap / dichloromethane / 15 h / 20 °C

7: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 20 °C

8: toluene-4-sulfonic acid / dichloromethane / 0.75 h / 20 °C

9: lithium borohydride / tetrahydrofuran / 7.25 h / -13 - 0 °C / Cooling with ice/water/ammonium chloride

10: dicyclohexyl-carbodiimide / dichloromethane; toluene / 23 h / 20 °C

With 1H-imidazole; dmap; sodium tetrahydroborate; lithium borohydride; tetra-n-propylammonium perruthenate.; tetrabutyl ammonium fluoride; water; 4-methylmorpholine N-oxide; dicyclohexyl-carbodiimide; hydrazine; toluene-4-sulfonic acid; In tetrahydrofuran; methanol; ethanol; dichloromethane; Isopropyl acetate; N,N-dimethyl-formamide; toluene;

upstream raw materials:

iso-butyl sidechain acid

7,9-anisaldehyde acetal-9-desoxo-10-epi-baccatin III

2-O-TBDMS-9-α-OH-9-desoxo-10-epi-paclitaxel

9-desoxo-7,9-anisaldehyde acetal 10-epipaclitaxel

Downstream raw materials:

9-α-hydroxy-10-α-acetyl-2'(R,S)-hydroxy-3'(S)-isobutyl-3'-(N-t-butoxycarbonyl)-taxane

C₄₃H₆₁NO₁₅

C₄₃H₆₁NO₁₅