Ethyl 6-bromopyridine-2-carboxylate

Base Information

Chemical Name:Ethyl 6-bromopyridine-2-carboxylate
CAS No.:21190-88-5
Molecular Formula:C8H8BrNO2
Molecular Weight:230.061
Hs Code.:2933399090
European Community (EC) Number:673-818-4
DSSTox Substance ID:DTXSID00374495
Nikkaji Number:J980.830B
Wikidata:Q72473347
Mol file:21190-88-5.mol

Synonyms:21190-88-5;ethyl 6-bromopyridine-2-carboxylate;ethyl 6-bromopicolinate;6-Bromopyridine-2-carboxylic acid ethyl ester;Ethyl 6-bromo-2-pyridinecarboxylate;2-Pyridinecarboxylic acid, 6-bromo-, ethyl ester;6-Bromopicolinic Acid Ethyl Ester;ethyl6-bromopyridine-2-carboxylate;ethyl-6-bromo-2-pyridinecarboxylate;MFCD04116913;6-bromo-pyridine-2-carboxylic acid ethyl ester;ethyl-6-bromopicolinate;ethyl6-bromopicolinate;2-Bromo-pyridine-6-carboxylicacidethylester;Ethyl 6-Bromo-2-picolinate;SCHEMBL198054;DTXSID00374495;OONBOXSIWCBAHZ-UHFFFAOYSA-N;ethyl-6-bromopyridine-2-carboxylate;Ethyl 6-bromopicolinate, AldrichCPR;AKOS015834714;AC-4401;CS-W003195;AS-12175;SY004812;A4582;AM20061686;E0826;FT-0648080;2-Bromo-6-pyridine-carboxylic acid ethyl ester;EN300-1232727;W-206602;ethyl 6-bromopicolinate,6-bromopyridine-2-ethyl formate;Z1209388585

Suppliers and Price of Ethyl 6-bromopyridine-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl6-Bromopicolinate
2.5g
$ 75.00

TCI Chemical
Ethyl 6-Bromopyridine-2-carboxylate >98.0%(GC)
5g
$ 50.00

SynQuest Laboratories
Ethyl 6-bromopyridine-2-carboxylate 98%
25 g
$ 120.00

SynQuest Laboratories
Ethyl 6-bromopyridine-2-carboxylate 98%
5 g
$ 64.00

Medical Isotopes, Inc.
Ethyl 6-Bromopyridine-2-carboxylate 95+%
10 g
$ 333.00

Matrix Scientific
Ethyl 6-bromopyridine-2-carboxylate 95+%
10g
$ 102.00

Matrix Scientific
Ethyl 6-bromopyridine-2-carboxylate 95+%
5g
$ 55.00

Matrix Scientific
Ethyl 6-bromopyridine-2-carboxylate 95+%
25g
$ 300.00

Chemenu
Ethyl 6-Bromopyridine-2-carboxylate 98%
100g
$ 184.00

American Custom Chemicals Corporation
ETHYL 6-BROMO-2-PYRIDINECARBOXYLATE 95.00%
25G
$ 1221.41

Total 81 raw suppliers

Chemical Property of Ethyl 6-bromopyridine-2-carboxylate

Chemical Property:

Vapor Pressure:0.000973mmHg at 25°C
Melting Point:41-42 °C
Refractive Index:1.544
Boiling Point:302.7 °C at 760 mmHg
PKA:-0.89±0.10(Predicted)
Flash Point:136.9 °C
PSA：39.19000
Density:1.501 g/cm³
LogP:2.02080
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:228.97384
Heavy Atom Count:12
Complexity:163

Purity/Quality:

98%, ^*data from raw suppliers

Ethyl6-Bromopicolinate ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=NC(=CC=C1)Br
Uses ethyl 6-bromopicolinate is a model compound for the preliminary screening of dimerization reaction.

Technology Process of Ethyl 6-bromopyridine-2-carboxylate

There total 7 articles about Ethyl 6-bromopyridine-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 21190-88-5
6-bromopyridine-2-carboxylic acid ethyl ester

Guidance literature:: With sodium hydride; In tetrahydrofuran; mineral oil; at 20 - 60 ℃; for 18h;

With hydrogenchloride; sulfuric acid; In tetrahydrofuran; water; mineral oil; at 60 ℃; for 18h;

Reference yield: 92.0%

: 21190-87-4
6-bromo-pyridine-2-carboxylic acid

: 64-17-5
ethanol

: 21190-88-5
6-bromopyridine-2-carboxylic acid ethyl ester

Guidance literature:: With sulfuric acid; Heating;
DOI:10.1002/chem.19970030116

Reference yield: 79.0%

: 626-05-1
2,6-Dibromopyridine

: 109-94-4
formic acid ethyl ester

: 21190-88-5
6-bromopyridine-2-carboxylic acid ethyl ester

Guidance literature:: 2,6-Dibromopyridine; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

formic acid ethyl ester; In tetrahydrofuran; hexane; at -78 ℃; for 3h;

With ethanol; iodine; potassium carbonate; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 14h;
DOI:10.1016/j.tet.2012.04.016