2-methyl-2H-pyrazole-3,4-dicarboxylic acid 4-dimethylamide 3-[(2-phenylimidazo[1,2-a]pyridin-7-yl)amide]

Base Information

Chemical Name:2-methyl-2H-pyrazole-3,4-dicarboxylic acid 4-dimethylamide 3-[(2-phenylimidazo[1,2-a]pyridin-7-yl)amide]
CAS No.:1278406-65-7
Molecular Formula:C₂₁H₂₀N₆O₂
Molecular Weight:388.429
Hs Code.:

Synonyms:2-methyl-2H-pyrazole-3,4-dicarboxylic acid 4-dimethylamide 3-[(2-phenylimidazo[1,2-a]pyridin-7-yl)amide]

Suppliers and Price of 2-methyl-2H-pyrazole-3,4-dicarboxylic acid 4-dimethylamide 3-[(2-phenylimidazo[1,2-a]pyridin-7-yl)amide]

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-methyl-2H-pyrazole-3,4-dicarboxylic acid 4-dimethylamide 3-[(2-phenylimidazo[1,2-a]pyridin-7-yl)amide]

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-methyl-2H-pyrazole-3,4-dicarboxylic acid 4-dimethylamide 3-[(2-phenylimidazo[1,2-a]pyridin-7-yl)amide]

There total 7 articles about 2-methyl-2H-pyrazole-3,4-dicarboxylic acid 4-dimethylamide 3-[(2-phenylimidazo[1,2-a]pyridin-7-yl)amide] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 1018814-40-8
7-bromo-2-phenylimidazo[1,2-α]pyridine

: 4-(dimethylaminocarbonyl)-1-methyl-1H-pyrazole-5-carboxamide

: 1278406-65-7
2-methyl-2H-pyrazole-3,4-dicarboxylic acid 4-dimethylamide 3-[(2-phenylimidazo[1,2-a]pyridin-7-yl)amide]

Guidance literature:: With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; potassium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In tetrahydrofuran; ethanol; at 80 ℃; for 3h; Inert atmosphere;

Reference yield:

: 81303-65-3
4-(ethoxycarbonyl)-1-methyl-1H-pyrazole-5-carboxylic acid

: 1278406-65-7
2-methyl-2H-pyrazole-3,4-dicarboxylic acid 4-dimethylamide 3-[(2-phenylimidazo[1,2-a]pyridin-7-yl)amide]

Guidance literature:: Multi-step reaction with 4 steps

1.1: 1,1'-carbonyldiimidazole / tetrahydrofuran / 2 h / 20 °C

1.2: 0.5 h / 10 °C

2.1: sodium hydroxide / tetrahydrofuran; water / 28 h / 20 °C

3.1: 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; N-ethyl-N,N-diisopropylamine / ethyl acetate / 2.5 h / 50 °C

4.1: tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; potassium carbonate / tetrahydrofuran; ethanol / 3 h / 80 °C / Inert atmosphere

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; potassium carbonate; 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; N-ethyl-N,N-diisopropylamine; 1,1'-carbonyldiimidazole; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; sodium hydroxide; In tetrahydrofuran; ethanol; water; ethyl acetate;

Reference yield:

: 5-carbamoyl-1-methyl-1H-pyrazole-4-carboxylic acid sodium salt

: 1278406-65-7
2-methyl-2H-pyrazole-3,4-dicarboxylic acid 4-dimethylamide 3-[(2-phenylimidazo[1,2-a]pyridin-7-yl)amide]

Guidance literature:: Multi-step reaction with 2 steps

1: 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; N-ethyl-N,N-diisopropylamine / ethyl acetate / 2.5 h / 50 °C

2: tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; potassium carbonate / tetrahydrofuran; ethanol / 3 h / 80 °C / Inert atmosphere

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; potassium carbonate; 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; N-ethyl-N,N-diisopropylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In tetrahydrofuran; ethanol; ethyl acetate;