(R)-ethyl 6-(7-methoxy-4-(1-phenylethylamino)quinazolin-6-yloxy)hexanoate

Base Information

Chemical Name:(R)-ethyl 6-(7-methoxy-4-(1-phenylethylamino)quinazolin-6-yloxy)hexanoate
CAS No.:1012057-67-8
Molecular Formula:C₂₅H₃₁N₃O₄
Molecular Weight:437.539
Hs Code.:

Synonyms:(R)-ethyl 6-(7-methoxy-4-(1-phenylethylamino)quinazolin-6-yloxy)hexanoate

Suppliers and Price of (R)-ethyl 6-(7-methoxy-4-(1-phenylethylamino)quinazolin-6-yloxy)hexanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (R)-ethyl 6-(7-methoxy-4-(1-phenylethylamino)quinazolin-6-yloxy)hexanoate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of (R)-ethyl 6-(7-methoxy-4-(1-phenylethylamino)quinazolin-6-yloxy)hexanoate

There total 6 articles about (R)-ethyl 6-(7-methoxy-4-(1-phenylethylamino)quinazolin-6-yloxy)hexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: 402734-23-0
(R)-7-methoxy-4-(1-phenylethylamino)quinazolin-6-ol

: 25542-62-5
6-bromo-hexanoic acid ethyl ester

: 1012057-67-8
(R)-ethyl 6-(7-methoxy-4-(1-phenylethylamino)quinazolin-6-yloxy)hexanoate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 3h;

Reference yield:

: 230955-75-6
6-acetoxy-4-chloro-7-methoxyquinazoline

: 1012057-67-8
(R)-ethyl 6-(7-methoxy-4-(1-phenylethylamino)quinazolin-6-yloxy)hexanoate

Guidance literature:: Multi-step reaction with 2 steps

1: isopropyl alcohol / 60 °C

2: potassium carbonate / N,N-dimethyl-formamide / 3 h / 60 °C

With potassium carbonate; In N,N-dimethyl-formamide; isopropyl alcohol;

Reference yield:

: 179688-52-9
6-hydroxy-7-methoxyquinazolin-4(3H)-one

: 1012057-67-8
(R)-ethyl 6-(7-methoxy-4-(1-phenylethylamino)quinazolin-6-yloxy)hexanoate

Guidance literature:: Multi-step reaction with 4 steps

1: pyridine / 3 h / Heating / reflux

2: trichlorophosphate / 3 h / Heating / reflux

3: isopropyl alcohol / 60 °C

4: potassium carbonate / N,N-dimethyl-formamide / 3 h / 60 °C

With pyridine; potassium carbonate; trichlorophosphate; In N,N-dimethyl-formamide; isopropyl alcohol;