2-methylcyclohexanone benzenesulfonylhydrazone

Base Information

• Chemical Name: 2-methylcyclohexanone benzenesulfonylhydrazone
• CAS No.: 56975-76-9
• Molecular Formula: C₁₃H₁₈N₂O₂S
• Molecular Weight: 266.364
• Mol file: 56975-76-9.mol

Synonyms:2-methylcyclohexanone benzenesulfonylhydrazone

Chemical Property of 2-methylcyclohexanone benzenesulfonylhydrazone

Chemical Property:

Purity/Quality:

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Technology Process of 2-methylcyclohexanone benzenesulfonylhydrazone

There total 1 articles about 2-methylcyclohexanone benzenesulfonylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

2-Methylcyclohexanone (583-60-8) + benzenesufonyl hydrazide (80-17-1) → 2-methylcyclohexanone benzenesulfonylhydrazone (56975-76-9)

Guidance literature:

With toluene-4-sulfonic acid; In ethanol; Heating;

DOI:10.1021/jo01303a020

Reference yield:

2-methylcyclohexanone benzenesulfonylhydrazone (56975-76-9) → 3-Methyl-1-(6-methyl-cyclohex-1-enyl)-but-2-en-1-one

Guidance literature:

Multi-step reaction with 2 steps

1: 1) n-BuLi / 1a) -45 deg C, b) 1-2h, RT, 2a) 0 deg C, 30 min., b) RT, several hours

2: AlCl₃ / CH₂Cl₂ / 0.25 h / -78 °C

With n-butyllithium; aluminium trichloride; In dichloromethane;

DOI:10.1021/jo01303a020

Reference yield:

chloro-trimethyl-silane (75-77-4) + 2-methylcyclohexanone benzenesulfonylhydrazone (56975-76-9) → 2-(trimethylsilyl)-3-methylcyclohexene (63031-68-5)

Guidance literature:

Multistep reaction; (i) alkyllithium, Me₂NCH₂CH₂NMe₂, (ii) /BRN= 1209232/;

DOI:10.1021/jo00402a043

upstream raw materials:

2-Methylcyclohexanone

benzenesufonyl hydrazide

Downstream raw materials:

2-(trimethylsilyl)-3-methylcyclohexene