trifluoro-methanesulfonic acid 2-(4-methoxy-benzyloxy)-2,3-dimethyl-1-methylene-pent-4-enyl ester

Base Information

• Chemical Name: trifluoro-methanesulfonic acid 2-(4-methoxy-benzyloxy)-2,3-dimethyl-1-methylene-pent-4-enyl ester
• CAS No.: 958019-01-7
• Molecular Formula: C₁₇H₂₁F₃O₅S
• Molecular Weight: 394.412
• Mol file: 958019-01-7.mol

Synonyms:trifluoro-methanesulfonic acid 2-(4-methoxy-benzyloxy)-2,3-dimethyl-1-methylene-pent-4-enyl ester

Chemical Property of trifluoro-methanesulfonic acid 2-(4-methoxy-benzyloxy)-2,3-dimethyl-1-methylene-pent-4-enyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of trifluoro-methanesulfonic acid 2-(4-methoxy-benzyloxy)-2,3-dimethyl-1-methylene-pent-4-enyl ester

There total 1 articles about trifluoro-methanesulfonic acid 2-(4-methoxy-benzyloxy)-2,3-dimethyl-1-methylene-pent-4-enyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

3-(4-methoxy-benzyloxy)-3,4-dimethyl-hex-5-en-2-one + N,N-phenylbistrifluoromethane-sulfonimide (37595-74-7) → trifluoro-methanesulfonic acid 2-(4-methoxy-benzyloxy)-2,3-dimethyl-1-methylene-pent-4-enyl ester (958019-01-7)

Guidance literature:

3-(4-methoxy-benzyloxy)-3,4-dimethyl-hex-5-en-2-one; With potassium hexamethylsilazane; In tetrahydrofuran; at 0 ℃; for 0.75h;

N,N-phenylbistrifluoromethane-sulfonimide; In tetrahydrofuran; at -78 - 20 ℃; Further stages.;

DOI:10.1021/ol701697r

Reference yield: 22.0%

methanol (67-56-1) + trifluoro-methanesulfonic acid 2-(4-methoxy-benzyloxy)-2,3-dimethyl-1-methylene-pent-4-enyl ester (958019-01-7) + carbon monoxide (201230-82-2) → 3-(4-methoxy-benzyloxy)-3,4-dimethyl-2-methylene-hex-5-enoic acid methyl ester + 1-(1,2-dimethyl-3,4-dimethylene-cyclobutoxymethyl)-4-methoxybenzene + 1-(1,2-dimethyl-5-methylene-cyclopent-3-enyloxymethyl)-4-methoxy-benzene + 1-(1,2-dimethyl-5-methylene-cyclopent-3-enyloxymethyl)-4-methoxy-benzene

Guidance literature:

With triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In N,N-dimethyl-formamide; at 50 ℃; Further byproducts.;

DOI:10.1021/ol701697r

Reference yield:

trifluoro-methanesulfonic acid 2-(4-methoxy-benzyloxy)-2,3-dimethyl-1-methylene-pent-4-enyl ester (958019-01-7) → 1-(1,2-dimethyl-3,4-dimethylene-cyclobutoxymethyl)-4-methoxybenzene + 1-(1,2-dimethyl-3,4-dimethylene-cyclobutoxymethyl)-4-methoxybenzene + 1-(1,2-dimethyl-5-methylene-cyclopent-3-enyloxymethyl)-4-methoxy-benzene + 1-(1,2-dimethyl-5-methylene-cyclopent-3-enyloxymethyl)-4-methoxy-benzene

Guidance literature:

With triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In methanol; N,N-dimethyl-formamide; at 50 ℃;

DOI:10.1021/ol701697r

upstream raw materials:

N,N-phenylbistrifluoromethane-sulfonimide