methyl (2S)-3-{3-[(2S)-3-methoxy-2-methyl-3-oxopropyl]phenyl}-2-methylpropanoate

Base Information

Chemical Name:methyl (2S)-3-{3-[(2S)-3-methoxy-2-methyl-3-oxopropyl]phenyl}-2-methylpropanoate
CAS No.:873326-10-4
Molecular Formula:C₁₆H₂₂O₄
Molecular Weight:278.348
Hs Code.:

Synonyms:methyl (2S)-3-{3-[(2S)-3-methoxy-2-methyl-3-oxopropyl]phenyl}-2-methylpropanoate

Suppliers and Price of methyl (2S)-3-{3-[(2S)-3-methoxy-2-methyl-3-oxopropyl]phenyl}-2-methylpropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl (2S)-3-{3-[(2S)-3-methoxy-2-methyl-3-oxopropyl]phenyl}-2-methylpropanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl (2S)-3-{3-[(2S)-3-methoxy-2-methyl-3-oxopropyl]phenyl}-2-methylpropanoate

There total 3 articles about methyl (2S)-3-{3-[(2S)-3-methoxy-2-methyl-3-oxopropyl]phenyl}-2-methylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 873326-09-1
(2S)-3-{3-[(2S)-2-carboxypropyl]phenyl}-2-methylpropanoic acid

: 67-56-1
methanol

: 873326-10-4
methyl (2S)-3-{3-[(2S)-3-methoxy-2-methyl-3-oxopropyl]phenyl}-2-methylpropanoate

Guidance literature:: With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 23 ℃; for 6h;
DOI:10.1002/chem.200500319

Reference yield:

: 873326-08-0
(4R)-4-benzyl-3-[(2S)-3-(3-{(2S)-3-[(4R)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]-2-methyl-3-oxopropyl}phenyl)-2-methylpropanoyl]-1,3-oxazolidin-2-one

: 873326-10-4
methyl (2S)-3-{3-[(2S)-3-methoxy-2-methyl-3-oxopropyl]phenyl}-2-methylpropanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / aq. H₂O₂; LiOH / tetrahydrofuran / 5 h / 0 °C

2: 71 percent / DCC; DMAP / CH₂Cl₂ / 6 h / 23 °C

With dmap; lithium hydroxide; dihydrogen peroxide; dicyclohexyl-carbodiimide; In tetrahydrofuran; dichloromethane;
DOI:10.1002/chem.200500319

Reference yield:

: 626-15-3
1,3-bis-(bromomethyl)benzene

: 873326-10-4
methyl (2S)-3-{3-[(2S)-3-methoxy-2-methyl-3-oxopropyl]phenyl}-2-methylpropanoate

Guidance literature:: Multi-step reaction with 3 steps

1.1: LDA / tetrahydrofuran; hexane / 1.5 h / -78 °C

1.2: 58 percent / tetrahydrofuran; hexane / 24 h / -78 - 23 °C

2.1: 90 percent / aq. H₂O₂; LiOH / tetrahydrofuran / 5 h / 0 °C

3.1: 71 percent / DCC; DMAP / CH₂Cl₂ / 6 h / 23 °C

With dmap; lithium hydroxide; dihydrogen peroxide; dicyclohexyl-carbodiimide; lithium diisopropyl amide; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.1002/chem.200500319