N-((4-methylphenyl)methyl)-N-(1-piperidin-4-yl)-4-chlorophenylacetamide

Base Information

Chemical Name:N-((4-methylphenyl)methyl)-N-(1-piperidin-4-yl)-4-chlorophenylacetamide
CAS No.:359878-09-4
Molecular Formula:C₂₁H₂₅ClN₂O
Molecular Weight:356.895
Hs Code.:

Synonyms:N-((4-methylphenyl)methyl)-N-(1-piperidin-4-yl)-4-chlorophenylacetamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-((4-methylphenyl)methyl)-N-(1-piperidin-4-yl)-4-chlorophenylacetamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

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Technology Process of N-((4-methylphenyl)methyl)-N-(1-piperidin-4-yl)-4-chlorophenylacetamide

There total 8 articles about N-((4-methylphenyl)methyl)-N-(1-piperidin-4-yl)-4-chlorophenylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 359879-83-7
2-(4-chlorophenyl)-N-(4-methylbenzyl)-N-(1-trifluoroacetylpiperidin-4-yl)acetamide

: 359878-09-4
N-((4-methylphenyl)methyl)-N-(1-piperidin-4-yl)-4-chlorophenylacetamide

Guidance literature:: With potassium carbonate; In methanol; for 24h;

Reference yield:

: C₂₆H₃₃ClN₂O₃

: 359878-09-4
N-((4-methylphenyl)methyl)-N-(1-piperidin-4-yl)-4-chlorophenylacetamide

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; diethyl ether; at 20 ℃; for 2h;

Reference yield:

: 104-84-7
para-methylbenzylamine

: 359878-09-4
N-((4-methylphenyl)methyl)-N-(1-piperidin-4-yl)-4-chlorophenylacetamide

Guidance literature:: Multi-step reaction with 3 steps

1: acetic acid; sodium cyanoborohydride / methanol / 20 h / 20 °C

2: N-ethyl-N,N-diisopropylamine / dichloromethane / 20 h / 20 °C

3: hydrogenchloride / 1,4-dioxane; diethyl ether / 2 h / 20 °C

With hydrogenchloride; sodium cyanoborohydride; acetic acid; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; methanol; diethyl ether; dichloromethane;