3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine

Base Information

Chemical Name:3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine
CAS No.:20348-23-6
Molecular Formula:C7H8N2O
Molecular Weight:136.153
Hs Code.:2934999090
European Community (EC) Number:664-149-9
ChEMBL ID:CHEMBL4582555
DSSTox Substance ID:DTXSID00526437
Wikidata:Q72466064
Mol file:20348-23-6.mol

Synonyms:20348-23-6;3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine;3,4-Dihydro-2H-pyrido[3,2-b]-1,4-oxazine;2H-PYRIDO[3,2-B]-1,4-OXAZINE, 3,4-DIHYDRO-;2H,3H,4H-pyrido[3,2-b][1,4]oxazine;MFCD09025907;dihydropyrido[1,4]oxazine;2H-Pyrido[3,2-b]-1,4-oxazine,3,4-dihydro-;SCHEMBL1093026;CHEMBL4582555;AMY2002;DTXSID00526437;CHEBI:194712;QQVXDMFULJVZLA-UHFFFAOYSA-N;AKOS005073314;AB49130;LD-0717;SY008040;A4428;CS-0039841;EN300-79568;J-511180;2-CHLORO-N-[4-(DIMETHYLAMINO)PHENYL]PROPANAMIDEHYDROCHLORIDE;3 pound not4-Dihydro-2H-pyrido[3 pound not2-b]-1 pound not4-oxazine

Suppliers and Price of 3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3,4-Dihydro-2h-pyrido[3,2-b][1,4]oxazine
250mg
$ 75.00

SynQuest Laboratories
3,4-Dihydro-2H-pyrido[3,2-b][1,4]oxazine
1 g
$ 232.00

SynQuest Laboratories
3,4-Dihydro-2H-pyrido[3,2-b][1,4]oxazine
500 mg
$ 176.00

SynQuest Laboratories
3,4-Dihydro-2H-pyrido[3,2-b][1,4]oxazine
5 g
$ 600.00

Matrix Scientific
3,4-Dihydro-2H-pyrido[3,2-b][1,4]oxazine >95%
5g
$ 495.00

Matrix Scientific
3,4-Dihydro-2H-pyrido[3,2-b][1,4]oxazine >95%
500mg
$ 65.00

Matrix Scientific
3,4-Dihydro-2H-pyrido[3,2-b][1,4]oxazine >95%
1g
$ 159.00

J&W Pharmlab
3,4-Dihydro-2H-pyrido[3,2-b][1,4]oxazine 96%
1g
$ 90.00

J&W Pharmlab
3,4-Dihydro-2H-pyrido[3,2-b][1,4]oxazine 96%
5g
$ 245.00

Crysdot
3,4-Dihydro-2H-pyrido[3,2-b][1,4]oxazine 98%
25g
$ 742.00

Total 22 raw suppliers

Chemical Property of 3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine

Chemical Property:

Vapor Pressure:0.003mmHg at 25°C
Melting Point:85 °C
Refractive Index:1.545
Boiling Point:285.731 °C at 760 mmHg
PKA:9.82±0.20(Predicted)
Flash Point:126.606 °C
PSA：34.15000
Density:1.168 g/cm³
LogP:1.02390
Storage Temp.:2-8°C(protect from light)
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:136.063662883
Heavy Atom Count:10
Complexity:118

Purity/Quality:

99%, ^*data from raw suppliers

3,4-Dihydro-2h-pyrido[3,2-b][1,4]oxazine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC2=C(N1)N=CC=C2

Technology Process of 3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine

There total 7 articles about 3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 20348-09-8
4H-pyrido[3,2-b][1,4]oxazin-3-one

: 20348-23-6
3,4-dihydro-2H-pyrido[3,2-b ][1,4]oxazine

Guidance literature:: 4H-pyrido[3,2-b][1,4]oxazin-3-one; With lithium aluminium tetrahydride; In tetrahydrofuran; for 18h; Heating / reflux;

With sodium hydroxide; water; In tetrahydrofuran; at 0 ℃;

Reference yield: 17.0%

: trans-2-(trifluoromethyl)cyclopropylboronic acid MIDA ester

: 34950-82-8
7-bromo-3,4-dihydro-2H-pyrido[3,2-β][1,4]oxazine

: 20348-23-6
3,4-dihydro-2H-pyrido[3,2-b ][1,4]oxazine

: trans-7-(2-(trifluoromethyl)cyclopropyl)-3,4-dihydro-2-pyrido[3,2-b][1,4]oxazine

Guidance literature:: With potassium carbonate; tricyclohexylphosphine; palladium diacetate; In water; toluene; at 115 ℃; for 96h; Inert atmosphere; Sealed tube;