[8-chloro-7-(4-fluorophenyl)-7H-12-oxa-9,11-diazabenzo[a]anthracen-10-yl]dimethylamine

Base Information

• Chemical Name: [8-chloro-7-(4-fluorophenyl)-7H-12-oxa-9,11-diazabenzo[a]anthracen-10-yl]dimethylamine
• CAS No.: 916079-55-5
• Molecular Formula: C₂₃H₁₇ClFN₃O
• Molecular Weight: 405.859
• Mol file: 916079-55-5.mol

Synonyms:[8-chloro-7-(4-fluorophenyl)-7H-12-oxa-9,11-diazabenzo[a]anthracen-10-yl]dimethylamine

Chemical Property of [8-chloro-7-(4-fluorophenyl)-7H-12-oxa-9,11-diazabenzo[a]anthracen-10-yl]dimethylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [8-chloro-7-(4-fluorophenyl)-7H-12-oxa-9,11-diazabenzo[a]anthracen-10-yl]dimethylamine

There total 3 articles about [8-chloro-7-(4-fluorophenyl)-7H-12-oxa-9,11-diazabenzo[a]anthracen-10-yl]dimethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

dichloromethylenedimethyliminium chloride (33842-02-3,529510-96-1) + 2-amino-4-(4-fluorophenyl)-4H-benzo[h]chromene-3-carbonitrile (326915-26-8) → [8-chloro-7-(4-fluorophenyl)-7H-12-oxa-9,11-diazabenzo[a]anthracen-10-yl]dimethylamine (916079-55-5)

Guidance literature:

In 1,2-dichloro-ethane; at 20 ℃;

DOI:10.1515/HC.2006.12.1.73

Reference yield:

α-naphthol (90-15-3) → [8-chloro-7-(4-fluorophenyl)-7H-12-oxa-9,11-diazabenzo[a]anthracen-10-yl]dimethylamine (916079-55-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / piperidine / ethanol / 5 h / Heating

2: 91 percent / 1,2-dichloro-ethane / 20 °C

With piperidine; In ethanol; 1,2-dichloro-ethane;

DOI:10.1515/HC.2006.12.1.73

Reference yield:

4-fluorobenzylidenemalononitrile (2826-22-4) → [8-chloro-7-(4-fluorophenyl)-7H-12-oxa-9,11-diazabenzo[a]anthracen-10-yl]dimethylamine (916079-55-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / piperidine / ethanol / 5 h / Heating

2: 91 percent / 1,2-dichloro-ethane / 20 °C

With piperidine; In ethanol; 1,2-dichloro-ethane;

DOI:10.1515/HC.2006.12.1.73

upstream raw materials:

dichloromethylenedimethyliminium chloride

2-amino-4-(4-fluorophenyl)-4H-benzo[h]chromene-3-carbonitrile

α-naphthol

4-fluorobenzylidenemalononitrile

Downstream raw materials:

[7-(4-fluorophenyl)-8-hydrazino-7H-12-oxa-9,11-diazabenzo[a]anthracen-10-yl]dimethylamine