ethyl 2-hydroxy-4-oxovalerate

Base Information

• Chemical Name: ethyl 2-hydroxy-4-oxovalerate
• CAS No.: 89941-79-7
• Molecular Formula: C₇H₁₂O₄
• Molecular Weight: 160.17
• Mol file: 89941-79-7.mol

Synonyms:ethyl 2-hydroxy-4-oxovalerate

Chemical Property of ethyl 2-hydroxy-4-oxovalerate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ethyl 2-hydroxy-4-oxovalerate

There total 1 articles about ethyl 2-hydroxy-4-oxovalerate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethanol (64-17-5) + ethyl 2,4-diketopentanoate (615-79-2) → ethyl 2-oxovalerate (50461-74-0) + ethyl 2-hydroxy-4-oxovalerate (89941-79-7)

Guidance literature:

Hydrogenation;

DOI:10.1021/jo01147a031

Reference yield:

ethyl 2-hydroxy-4-oxovalerate (89941-79-7) → 6-Methylpyridazin-3(2H)-on (13327-27-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 88 percent / 99percent hydrazine hydrate / aq. ethanol / 2 h / Ambient temperature

2: 75 percent / 10percent HCl / aq. ethanol / 2 h / Heating

With hydrogenchloride; hydrazine hydrate; In ethanol;

DOI:10.1055/s-1994-25663

Reference yield:

ethyl 2-hydroxy-4-oxovalerate (89941-79-7) → 4-oxo-2-pentenoic acid (4743-82-2)

Guidance literature:

DOI:10.1002/hlca.19470300616

upstream raw materials:

ethanol

ethyl 2,4-diketopentanoate

Downstream raw materials:

4-oxo-2-pentenoic acid

6-Methylpyridazin-3(2H)-on