1-(4-Fluoro-3-methoxyphenyl)ethanone

Base Information

Chemical Name:1-(4-Fluoro-3-methoxyphenyl)ethanone
CAS No.:64287-19-0
Molecular Formula:C9H9FO2
Molecular Weight:168.168
Hs Code.:2914700090
DSSTox Substance ID:DTXSID40379080
Wikidata:Q72474235

Synonyms:64287-19-0;1-(4-fluoro-3-methoxyphenyl)ethanone;4'-Fluoro-3'-methoxyacetophenone;4-Fluoro-3-Methoxyacetophenone;1-(4-Fluoro-3-methoxyphenyl)ethan-1-one;ethanone, 1-(4-fluoro-3-methoxyphenyl)-;MFCD00272135;3-METHOXY-4-FLUOROACETOPHENONE;SCHEMBL660929;DTXSID40379080;PFEGFUCYOHBDJF-UHFFFAOYSA-N;CK2585;AKOS005063602;AC-3642;CS-W017813;FS-1315;AC-23837;AM20080776;FT-0640938;4'-Fluoro-3'-methoxyacetophenone, AldrichCPR;A19711;EN300-120850;5-NITRO-1-BENZOTHIOPHENE-2-CARBONYLCHLORIDE;Z1201620068

Suppliers and Price of 1-(4-Fluoro-3-methoxyphenyl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4''-Fluoro-3''-methoxyacetophenone
1g
$ 100.00

TRC
4''-Fluoro-3''-methoxyacetophenone
100mg
$ 45.00

SynQuest Laboratories
4'-Fluoro-3'-methoxyacetophenone 98%
1 g
$ 56.00

SynQuest Laboratories
4'-Fluoro-3'-methoxyacetophenone 98%
5 g
$ 178.00

SynQuest Laboratories
4'-Fluoro-3'-methoxyacetophenone 98%
10 g
$ 304.00

Crysdot
1-(4-Fluoro-3-methoxyphenyl)ethanone 98%
5g
$ 220.00

Crysdot
1-(4-Fluoro-3-methoxyphenyl)ethanone 98%
1g
$ 92.00

Apolloscientific
4'-Fluoro-3'-methoxyacetophenone 98%
1g
$ 51.00

Apolloscientific
4'-Fluoro-3'-methoxyacetophenone 98%
10g
$ 276.00

Apolloscientific
4'-Fluoro-3'-methoxyacetophenone 98%
5g
$ 161.00

Total 49 raw suppliers

Chemical Property of 1-(4-Fluoro-3-methoxyphenyl)ethanone

Chemical Property:

Vapor Pressure:0.0159mmHg at 25°C
Melting Point:52 °C
Refractive Index:1.51
Boiling Point:246 °C at 760 mmHg
Flash Point:99.6 °C
PSA：26.30000
Density:1.127g/cm³
LogP:2.03690
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:168.05865769
Heavy Atom Count:12
Complexity:170

Purity/Quality:

97% ^*data from raw suppliers

4''-Fluoro-3''-methoxyacetophenone ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,Xn
Statements: 36/37/38-22
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=CC(=C(C=C1)F)OC
Uses 4''-Fluoro-3''-methoxyacetophenone

Technology Process of 1-(4-Fluoro-3-methoxyphenyl)ethanone

There total 5 articles about 1-(4-Fluoro-3-methoxyphenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 1262882-70-1
4-fluoro-N,3-dimethoxy-N-methylbenzamide

: 75-16-1
methylmagnesium bromide

: 64287-19-0
1-(4-fluoro-3-methoxy-phenyl)ethanone

Guidance literature:: In tetrahydrofuran; at 0 ℃; for 0.25h; Inert atmosphere;

Reference yield: 92.0%

: 949159-95-9
1-(4-fluoro-3-hydroxyphenyl)ethan-1-one

: 74-88-4
methyl iodide

: 64287-19-0
1-(4-fluoro-3-methoxy-phenyl)ethanone

Guidance literature:: With sodium carbonate; In N,N-dimethyl-formamide; at 90 ℃;

Reference yield:

: 82846-18-2
4?fluoro-3-methoxybenzoic acid

: 64287-19-0
1-(4-fluoro-3-methoxy-phenyl)ethanone

Guidance literature:: Multi-step reaction with 2 steps

1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / dichloromethane / 36 h / 20 °C

2: tetrahydrofuran / 0.25 h / 0 °C / Inert atmosphere

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In tetrahydrofuran; dichloromethane;