4-(3-(4-Methoxyphenoxy)-3-phenylpropyl)morpholine

Base Information

Chemical Name:4-(3-(4-Methoxyphenoxy)-3-phenylpropyl)morpholine
CAS No.:157846-74-7
Molecular Formula:C₂₀H₂₅NO₃
Molecular Weight:327.423
Hs Code.:
DSSTox Substance ID:DTXSID50935818
Mol file:157846-74-7.mol

Synonyms:4-(3-(4-Methoxyphenoxy)-3-phenylpropyl)morpholine;Morpholine, 4-(3-(4-methoxyphenoxy)-3-phenylpropyl)-;157846-74-7;4-[3-(4-methoxyphenoxy)-3-phenylpropyl]morpholine;DTXSID50935818;LS-93117

Suppliers and Price of 4-(3-(4-Methoxyphenoxy)-3-phenylpropyl)morpholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of 4-(3-(4-Methoxyphenoxy)-3-phenylpropyl)morpholine

Chemical Property:

Vapor Pressure:2.79E-09mmHg at 25°C
Boiling Point:477.5°Cat760mmHg
Flash Point:138.5°C
Density:1.104g/cm³
XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:327.18344366
Heavy Atom Count:24
Complexity:332

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)OC(CCN2CCOCC2)C3=CC=CC=C3

Technology Process of 4-(3-(4-Methoxyphenoxy)-3-phenylpropyl)morpholine

There total 4 articles about 4-(3-(4-Methoxyphenoxy)-3-phenylpropyl)morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2298-48-8
3-morpholin-4-yl-1-phenyl-propan-1-one

: 157846-74-7
4-[3-(4-Methoxy-phenoxy)-3-phenyl-propyl]-morpholine

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / NaBH₄ / methanol

2: 59 percent / K₂CO₃ / acetone / 24 h / 0 - 4 °C

3: 1.) NaOH / 1.) aq. EtOH, 32 deg C, 10 min, 2.) aq. EtOH, 32 deg C, 48 h

With sodium hydroxide; sodium tetrahydroborate; potassium carbonate; In methanol; acetone;

Reference yield:

: 4441-34-3
3-morpholino-1-phenylpropan-1-ol

: 157846-74-7
4-[3-(4-Methoxy-phenoxy)-3-phenyl-propyl]-morpholine

Guidance literature:: Multi-step reaction with 2 steps

1: 59 percent / K₂CO₃ / acetone / 24 h / 0 - 4 °C

2: 1.) NaOH / 1.) aq. EtOH, 32 deg C, 10 min, 2.) aq. EtOH, 32 deg C, 48 h

With sodium hydroxide; potassium carbonate; In acetone;

Reference yield:

: 98-86-2
acetophenone

: 157846-74-7
4-[3-(4-Methoxy-phenoxy)-3-phenyl-propyl]-morpholine

Guidance literature:: Multi-step reaction with 4 steps

1: 75 percent / conc. HCl / ethanol / 6 h / Heating

2: 80 percent / NaBH₄ / methanol

3: 59 percent / K₂CO₃ / acetone / 24 h / 0 - 4 °C

4: 1.) NaOH / 1.) aq. EtOH, 32 deg C, 10 min, 2.) aq. EtOH, 32 deg C, 48 h

With hydrogenchloride; sodium hydroxide; sodium tetrahydroborate; potassium carbonate; In methanol; ethanol; acetone;