3,4-Difluorostyrene

Base Information

Chemical Name:3,4-Difluorostyrene
CAS No.:405-03-8
Molecular Formula:C8H6F2
Molecular Weight:140.132
Hs Code.:2903999090
European Community (EC) Number:812-993-5
DSSTox Substance ID:DTXSID10607963
Wikidata:Q72464280
Mol file:405-03-8.mol

Synonyms:3,4-Difluorostyrene;405-03-8;1,2-difluoro-4-vinylbenzene;4-ethenyl-1,2-difluorobenzene;3,4-Difluorostyene;SCHEMBL248639;1,2-Difluoro-4-vinyl-benzene;SCHEMBL13158926;DTXSID10607963;VPKZWIGZODEBDP-UHFFFAOYSA-N;MFCD09038471;4-ethenyl-1,2-bis(fluoranyl)benzene;AKOS006330038;PS-9046;CS-0113814;EN300-1243671;A825140

Suppliers and Price of 3,4-Difluorostyrene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3,4-Difluorostyrene
1g
$ 330.00

SynQuest Laboratories
3,4-Difluorostyrene
25 g
$ 616.00

Crysdot
1,2-Difluoro-4-vinylbenzene 95+%
10g
$ 338.00

Crysdot
1,2-Difluoro-4-vinylbenzene 95+%
25g
$ 608.00

Biosynth Carbosynth
3,4-Difluorostyrene
10 g
$ 550.00

Biosynth Carbosynth
3,4-Difluorostyrene
5 g
$ 350.00

Biosynth Carbosynth
3,4-Difluorostyrene
2 g
$ 200.00

Biosynth Carbosynth
3,4-Difluorostyrene
1 g
$ 125.00

Biosynth Carbosynth
3,4-Difluorostyrene
500 mg
$ 75.00

Apolloscientific
3,4-Difluorostyrene
5g
$ 232.00

Total 27 raw suppliers

Chemical Property of 3,4-Difluorostyrene

Chemical Property:

Vapor Pressure:5.83mmHg at 25°C
Refractive Index:1.512
Boiling Point:146.5 °C at 760 mmHg
Flash Point:31.7 °C
PSA：0.00000
Density:1.131 g/cm³
LogP:2.60780
Storage Temp.:Sealed in dry,Store in freezer, under -20°C
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:140.04375652
Heavy Atom Count:10
Complexity:122

Purity/Quality:

99%, ^*data from raw suppliers

3,4-Difluorostyrene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C=CC1=CC(=C(C=C1)F)F
Uses 3,4-Difluorostyrene is a building block used to prepare pyrazole derivatives as JNK inhibitors.

Technology Process of 3,4-Difluorostyrene

There total 4 articles about 3,4-Difluorostyrene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 321318-21-2
1-(3,4-difluorophenyl)ethan-1-ol

: 405-03-8
1-(3,4-difluorophenyl)ethene

Guidance literature:: With sulfuric acid; In toluene; at 110 ℃; for 16h;

Reference yield:

: 34036-07-2
3,4 difluorobenzaldehyde

: 1779-49-3
Methyltriphenylphosphonium bromide

: 405-03-8
1-(3,4-difluorophenyl)ethene

Guidance literature:: With sodium hydride; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1021/jm801354e

Reference yield:

: 367-11-3
ortho-difluorobenzene

: 405-03-8
1-(3,4-difluorophenyl)ethene

Guidance literature:: Multi-step reaction with 3 steps

1: aluminum (III) chloride / 6 h / 30 °C

2: methanol; sodium tetrahydroborate / 3.2 h / 0 - 50 °C

3: sulfuric acid / toluene / 16 h / 110 °C

With methanol; aluminum (III) chloride; sodium tetrahydroborate; sulfuric acid; In toluene;