C₁₇H₂₀N₂O₂

Base Information

• Chemical Name: C₁₇H₂₀N₂O₂
• CAS No.: 1332481-60-3
• Molecular Formula: C₁₇H₂₀N₂O₂
• Molecular Weight: 284.358
• Mol file: 1332481-60-3.mol

Synonyms:C₁₇H₂₀N₂O₂

Chemical Property of C₁₇H₂₀N₂O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₇H₂₀N₂O₂

There total 5 articles about C₁₇H₂₀N₂O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

N-(2-methoxybenzyl)pyridine-2-amide (867350-21-8) + 1-iodo-propane (107-08-4) → C17H20N2O2 (1332481-60-3)

Guidance literature:

With oxygen; palladium diacetate; sodium triflate; potassium carbonate; In tert-Amyl alcohol; at 125 ℃; for 36h; under 760.051 Torr; regioselective reaction;

DOI:10.1021/ol201930e

Reference yield: 98.0%

C14H13(2)HN2O2 (1332481-87-4) + 1-iodo-propane (107-08-4) → C17H20N2O2 (1332481-60-3)

Guidance literature:

With oxygen; palladium diacetate; sodium triflate; potassium carbonate; In tert-Amyl alcohol; at 125 ℃; for 36h; under 760.051 Torr; regioselective reaction;

DOI:10.1021/ol201930e

Reference yield:

2-Picolinic acid (98-98-6) → C17H20N2O2 (1332481-60-3)

Guidance literature:

Multi-step reaction with 3 steps

1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 24 h / 20 °C

2: tert-butyl alcohol-d; deuteroacetic acid; palladium diacetate / 36 h / 125 °C

3: oxygen; palladium diacetate; sodium triflate; potassium carbonate / tert-Amyl alcohol / 36 h / 125 °C / 760.05 Torr

With tert-butyl alcohol-d; deuteroacetic acid; oxygen; palladium diacetate; sodium triflate; potassium carbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In tert-Amyl alcohol; N,N-dimethyl-formamide;

DOI:10.1021/ol201930e

upstream raw materials:

2-Picolinic acid

2-methoxybenzylamine

N-(2-methoxybenzyl)pyridine-2-amide

1-iodo-propane