2',3'-dimethoxyphenylacetyl chloride

Base Information

• Chemical Name: 2',3'-dimethoxyphenylacetyl chloride
• CAS No.: 6831-56-7
• Molecular Formula: C₁₀H₁₁ClO₃
• Molecular Weight: 214.649
• Mol file: 6831-56-7.mol

Synonyms:2',3'-dimethoxyphenylacetyl chloride

Chemical Property of 2',3'-dimethoxyphenylacetyl chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2',3'-dimethoxyphenylacetyl chloride

There total 4 articles about 2',3'-dimethoxyphenylacetyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,3-dimethoxyphenylacetic acid (90-53-9) → 2',3'-dimethoxyphenylacetyl chloride (6831-56-7)

Guidance literature:

With thionyl chloride; for 24h; Heating;

DOI:10.1111/j.2042-7158.1992.tb03617.x

Reference yield:

2-(2,3-dimethoxyphenyl)acetonitrile (4468-57-9) → 2',3'-dimethoxyphenylacetyl chloride (6831-56-7)

Guidance literature:

Multi-step reaction with 2 steps

1: aq.-ethanolic KOH-solution

2: thionyl chloride

With potassium hydroxide; thionyl chloride;

DOI:10.1080/10473289.2000.10464134

Reference yield:

2,3-dimethoxybenzyl chloride (3893-01-4) → 2',3'-dimethoxyphenylacetyl chloride (6831-56-7)

Guidance literature:

Multi-step reaction with 3 steps

1: ethanol

2: aq.-ethanolic KOH-solution

3: thionyl chloride

With potassium hydroxide; thionyl chloride; ethanol;

DOI:10.1080/10473289.2000.10464134

upstream raw materials:

2,3-dimethoxyphenylacetic acid

2-(2,3-dimethoxyphenyl)acetonitrile

2,3-dimethoxybenzyl chloride

Downstream raw materials:

(2,3-dimethoxy-phenyl)-acetic acid amide

2-(2,3-Dimethoxy-phenyl)-N-isopropyl-acetamide

N-Butyl-2-(2,3-dimethoxy-phenyl)-acetamide

(2,3-dimethoxy-phenyl)-acetic acid-(2,3-dimethoxy-phenethylamide)