Trifluoro-methanesulfonic acid (E)-2-chloro-1-naphthalen-2-yl-2-(toluene-4-sulfinyl)-vinyl ester

Base Information

• Chemical Name: Trifluoro-methanesulfonic acid (E)-2-chloro-1-naphthalen-2-yl-2-(toluene-4-sulfinyl)-vinyl ester
• CAS No.: 155725-35-2
• Molecular Formula: C₂₀H₁₄ClF₃O₄S₂
• Molecular Weight: 474.909
• Mol file: 155725-35-2.mol

Synonyms:Trifluoro-methanesulfonic acid (E)-2-chloro-1-naphthalen-2-yl-2-(toluene-4-sulfinyl)-vinyl ester

Chemical Property of Trifluoro-methanesulfonic acid (E)-2-chloro-1-naphthalen-2-yl-2-(toluene-4-sulfinyl)-vinyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Trifluoro-methanesulfonic acid (E)-2-chloro-1-naphthalen-2-yl-2-(toluene-4-sulfinyl)-vinyl ester

There total 3 articles about Trifluoro-methanesulfonic acid (E)-2-chloro-1-naphthalen-2-yl-2-(toluene-4-sulfinyl)-vinyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

N,N-phenylbistrifluoromethane-sulfonimide (37595-74-7) + 2-chloro-2-(p-tolylsulfinyl)-1-(2-naphthyl)-1-ethanone (155725-33-0) → Trifluoro-methanesulfonic acid (E)-2-chloro-1-naphthalen-2-yl-2-(toluene-4-sulfinyl)-vinyl ester (155725-35-2)

Guidance literature:

With lithium diisopropyl amide; In N,N,N,N,N,N-hexamethylphosphoric triamide; 1,2-dimethoxyethane; Ambient temperature;

DOI:10.1246/cl.1994.567

Reference yield:

chloromethyl p-tolyl sulfoxide (24824-93-9) → Trifluoro-methanesulfonic acid (E)-2-chloro-1-naphthalen-2-yl-2-(toluene-4-sulfinyl)-vinyl ester (155725-35-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / LDA / tetrahydrofuran / -70 °C

2: 99 percent / LDA / 1,2-dimethoxy-ethane; hexamethylphosphoric acid triamide / Ambient temperature

With lithium diisopropyl amide; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; 1,2-dimethoxyethane;

DOI:10.1246/cl.1994.567

Reference yield:

methyl naphthalene-2-carboxylate (2459-25-8) → Trifluoro-methanesulfonic acid (E)-2-chloro-1-naphthalen-2-yl-2-(toluene-4-sulfinyl)-vinyl ester (155725-35-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / LDA / tetrahydrofuran / -70 °C

2: 99 percent / LDA / 1,2-dimethoxy-ethane; hexamethylphosphoric acid triamide / Ambient temperature

With lithium diisopropyl amide; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; 1,2-dimethoxyethane;

DOI:10.1246/cl.1994.567

upstream raw materials:

N,N-phenylbistrifluoromethane-sulfonimide

2-chloro-2-(p-tolylsulfinyl)-1-(2-naphthyl)-1-ethanone

chloromethyl p-tolyl sulfoxide

methyl naphthalene-2-carboxylate