(2,6-Dimethylpyridin-4-yl)methanol

Base Information

• Chemical Name: (2,6-Dimethylpyridin-4-yl)methanol
• CAS No.: 18088-01-2
• Molecular Formula: C8H11NO
• Molecular Weight: 137.181
• Hs Code.: 2933399090
• DSSTox Substance ID: DTXSID50396925
• Mol file: 18088-01-2.mol

Synonyms:(2,6-dimethylpyridin-4-yl)methanol;18088-01-2;2,6-Dimethyl-4-(hydroxymethyl)pyridine;(2,6-Dimethyl-pyridin-4-yl)-methanol;4-Pyridinemethanol, 2,6-dimethyl-;4-Pyridinemethanol,2,6-dimethyl-;MFCD00956275;4-(Hydroxymethyl)-2,6-dimethylpyridine;2,6-dimethyl-4-pyridinemethanol;SCHEMBL377724;DTXSID50396925;DLDGHMPQNVTNRC-UHFFFAOYSA-N;(2,6-dimethyl-4-pyridyl)methanol;(2,6-dimethyl-4-pyridinyl)methanol;BBL100736;STL554530;4-Hydroxymethyl-2,6-dimethylpyridine;AKOS005255193;AB86594;AM85637;AC-23055;TS-01776;FT-0685540;A812568;W-206290

Chemical Property of (2,6-Dimethylpyridin-4-yl)methanol

Chemical Property:

• Vapor Pressure: 0.018mmHg at 25°C
• Melting Point: 98 °C(Solv: cyclohexane (110-82-7))
• Refractive Index: 1.539
• Boiling Point: 242.7 °C at 760 mmHg
• PKA: 13.48±0.10(Predicted)
• Flash Point: 100.6 °C
• PSA: 33.12000
• Density: 1.063 g/cm³
• LogP: 1.19070
• Storage Temp.: Inert atmosphere,Room Temperature
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 137.084063974
• Heavy Atom Count: 10
• Complexity: 95.4

Purity/Quality:

98%,99%, ^*data from raw suppliers

(2,6-Dimethylpyridin-4-yl)methanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=CC(=N1)C)CO

Technology Process of (2,6-Dimethylpyridin-4-yl)methanol

There total 8 articles about (2,6-Dimethylpyridin-4-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

2,4,6-trimethyl-1-(2-methylpyrazol-1-io)pyridinium bistetrafluoroborate → 2,6-dimethyl-4-pyridinemethanol (18088-01-2)

Guidance literature:

With diethylamine; In chloroform; water; for 0.0166667h;

Reference yield: 41.0%

methanol (67-56-1) + 1-methoxy-2,6-dimethyl-pyridinium tetrafluoroborate → 2,6-dimethyl-4-pyridinemethanol (18088-01-2)

Guidance literature:

With ammonium persulfate; for 1h; Heating;

Reference yield: 40.0%

methanol (67-56-1) + 1-methoxy-2,6-dimethylpyridinium methyl sulfate (87117-15-5) → 2,6-dimethyl-4-pyridinemethanol (18088-01-2)

Guidance literature:

With ammonium persulfate; In water; for 1h; Reflux;

upstream raw materials:

methanol

2,6-dimethylpyridine

2,6-lutidine N-oxide

1-methoxy-2,6-dimethylpyridinium methyl sulfate

Downstream raw materials:

(1-{[2-(tert-Butyl-dimethyl-silanyloxy)-3,3,3-trifluoro-1-isopropyl-propylcarbamoyl]-methyl}-2-oxo-6-phenyl-1,2-dihydro-pyridin-3-yl)-carbamic acid 2,6-dimethyl-pyridin-4-ylmethyl ester

(2,6-dimethylpyridin-4-yl)methyl 4-nitrophenyl carbonate

(2,6-dimethylpyridin-4-yl)methyl (1-methyl-1-phenylethyl)carbamate hydrochloride

7-(2-(benzyloxy)ethoxy)-2-(2,6-dimethylpyridin-4-yl)-5-methoxyquinazolin-4(3H)-one

Refernces

• 1、 -. "NEW COMPOUNDS AND USES THEREOF FOR DETECTION OF TARGET MOLECULES IN A SAMPLE". . . Retrieved 2018/04/27.
• 2、 -. "Anti-inflammatory agents". . . Retrieved 2016/02/05.