2,3,4-TRIFLUOROBENZAMIDE

Base Information

• Chemical Name: 2,3,4-TRIFLUOROBENZAMIDE
• CAS No.: 207919-09-3
• Molecular Formula: C₇H₄F₃NO
• Molecular Weight: 175.11
• Hs Code.: 2924299090
• Mol file: 207919-09-3.mol

Synonyms:2,3,4-Trifluorobenzamide

Chemical Property of 2,3,4-TRIFLUOROBENZAMIDE

Chemical Property:

• Vapor Pressure: 1.83mmHg at 25°C
• Melting Point: 127-129oC
• Boiling Point: 166°C at 760 mmHg
• PKA: 14.65±0.50(Predicted)
• Flash Point: 54.2°C
• PSA: 43.09000
• Density: 1.45g/cm³
• LogP: 1.90310

Purity/Quality:

97% ^*data from raw suppliers

2,3,4-Trifluorobenzamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3,4-TRIFLUOROBENZAMIDE

There total 1 articles about 2,3,4-TRIFLUOROBENZAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

methanol (67-56-1) + propylamine (107-10-8,42939-71-9) + 3-methyl-5-(2,3,4-trifluorophenyl)-1,2,4-oxadiazole (740817-48-5) → 2,3,4-trifluorobenzamide (207919-09-3) + 3-methyl-1-propyl-5-(2,3,4-trifluoro-phenyl)-1H-[1,2,4]triazole + 5,6,7-trifluoro-2-methyl-3H-quinazolin-4-one

Guidance literature:

With oxygen; for 3h; Irradiation;

DOI:10.3987/COM-04-10255

Reference yield: 93.0%

2,3,4-trifluorobenzamide (207919-09-3) → 2,3,4-trifluorobenzonitrile (143879-80-5)

Guidance literature:

With trichlorophosphate; at 80 ℃; for 2h; Inert atmosphere;

DOI:10.1039/d0ob02484h

Reference yield: 54.0%

2,3,4-trifluorobenzamide (207919-09-3) + N-methylaniline (100-61-8) → C14H12F2N2O

Guidance literature:

2,3,4-trifluorobenzamide; N-methylaniline; With lithium amide; for 4h; Inert atmosphere;

With hydrogenchloride; In water; Inert atmosphere;

DOI:10.1021/op0501242

upstream raw materials:

methanol

propylamine

3-methyl-5-(2,3,4-trifluorophenyl)-1,2,4-oxadiazole

Downstream raw materials:

2,3,4-trifluorobenzonitrile

3-fluoro-2,4-dihydroxybenzaldehyde