N,N-Dimethyl-2-oxo-2,N'-diphenyl-acetamidine

Base Information

• Chemical Name: N,N-Dimethyl-2-oxo-2,N'-diphenyl-acetamidine
• CAS No.: 81977-59-5
• Molecular Formula: C₁₆H₁₆N₂O
• Molecular Weight: 252.316
• Mol file: 81977-59-5.mol

Synonyms:N,N-Dimethyl-2-oxo-2,N'-diphenyl-acetamidine

Chemical Property of N,N-Dimethyl-2-oxo-2,N'-diphenyl-acetamidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N-Dimethyl-2-oxo-2,N'-diphenyl-acetamidine

There total 9 articles about N,N-Dimethyl-2-oxo-2,N'-diphenyl-acetamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

N,N-dimethyl-formamide (68-12-2,33513-42-7) + aniline (62-53-3) + acetophenone (98-86-2) → N,N-Dimethyl-2-oxo-2,N'-diphenyl-acetamidine (81977-59-5)

Guidance literature:

With 1,10-Phenanthroline; di-tert-butyl peroxide; oxygen; Potassium benzoate; copper dichloride; at 120 ℃; for 36h; under 760.051 Torr; Reagent/catalyst; Temperature; Catalytic behavior; Mechanism;

DOI:10.1039/c9ra00616h

Reference yield: 80.0%

2-dimethylamino-1-phenyl-ethanone (3319-03-7) + aniline (62-53-3) → N,N-Dimethyl-2-oxo-2,N'-diphenyl-acetamidine (81977-59-5)

Guidance literature:

With 1,10-Phenanthroline; di-tert-butyl peroxide; oxygen; Potassium benzoate; copper dichloride; In dimethyl sulfoxide; at 120 ℃; for 36h; under 760.051 Torr;

DOI:10.1039/c9ra00616h

Reference yield: 43.0%

Dimethyl-(1-phenyl-vinyl)-amine (14548-16-4) + Nitrosobenzene (586-96-9) → N,N-Dimethyl-2-oxo-2,N'-diphenyl-acetamidine (81977-59-5) + aniline (62-53-3) + azoxybenzene (495-48-7,55599-32-1)

Guidance literature:

in benzene or ether, standing overnight;

upstream raw materials:

Dimethyl-(1-phenyl-vinyl)-amine

Nitrosobenzene

N,N-dimethyl-formamide

aniline

Downstream raw materials:

Acetic acid 2-(acetyl-phenyl-amino)-1-phenyl-ethyl ester

2-oxo-N,2-diphenylacetamide

1-phenyl-2-phenylaminoethanol

Refernces

• 1、 Koikov, L. N.,Terent'ev, P. B.,Yufit, D. S.,Struchkov, Yu. T.,Zubarev, V. E.. "New rearrangement in the reaction of 1-aryl-1-(dimethylamino)-ethylenes with nitrosobenzenes. Molecular and crystal structure of N1,N1-dimethyl-N2-phenyl-2-oxo(3-pyridyl)acetamidine". . p. 1664 - 1674. Retrieved 2007/10/02.