4'-methoxy-3-(2-methyl-1,8-naphthyridin-3-yl)-5-(piperidin-1-yl)biphenyl-4-carbonitrile

Base Information

Chemical Name:4'-methoxy-3-(2-methyl-1,8-naphthyridin-3-yl)-5-(piperidin-1-yl)biphenyl-4-carbonitrile
CAS No.:1632038-87-9
Molecular Formula:C₂₈H₂₆N₄O
Molecular Weight:434.541
Hs Code.:

Synonyms:4'-methoxy-3-(2-methyl-1,8-naphthyridin-3-yl)-5-(piperidin-1-yl)biphenyl-4-carbonitrile

Suppliers and Price of 4'-methoxy-3-(2-methyl-1,8-naphthyridin-3-yl)-5-(piperidin-1-yl)biphenyl-4-carbonitrile

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4'-methoxy-3-(2-methyl-1,8-naphthyridin-3-yl)-5-(piperidin-1-yl)biphenyl-4-carbonitrile

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 4'-methoxy-3-(2-methyl-1,8-naphthyridin-3-yl)-5-(piperidin-1-yl)biphenyl-4-carbonitrile

There total 3 articles about 4'-methoxy-3-(2-methyl-1,8-naphthyridin-3-yl)-5-(piperidin-1-yl)biphenyl-4-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 5174-87-8
1-(2-methyl-1,8-naphthyridin-3-yl)ethan-1-one

: 757235-52-2
6-(4-methoxyphenyl)-2-oxo-4-(piperidin-1-yl)-2H-pyran-3-carbonitrile

: 1632038-87-9
4'-methoxy-3-(2-methyl-1,8-naphthyridin-3-yl)-5-(piperidin-1-yl)biphenyl-4-carbonitrile

Guidance literature:: With potassium hydroxide; In N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere;
DOI:10.1055/s-0033-1339113

Reference yield:

: 100-06-1
1-(4-methoxyphenyl)ethanone

: 1632038-87-9
4'-methoxy-3-(2-methyl-1,8-naphthyridin-3-yl)-5-(piperidin-1-yl)biphenyl-4-carbonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: potassium hydroxide / dimethyl sulfoxide / 20 °C

2: methanol / Reflux

3: potassium hydroxide / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

With potassium hydroxide; In methanol; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1055/s-0033-1339113

Reference yield:

: 61380-86-7
6-(4-methoxyphenyl)-3-cyano-4-methylsulfanyl-2H-pyran-2-one

: 1632038-87-9
4'-methoxy-3-(2-methyl-1,8-naphthyridin-3-yl)-5-(piperidin-1-yl)biphenyl-4-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: methanol / Reflux

2: potassium hydroxide / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

With potassium hydroxide; In methanol; N,N-dimethyl-formamide;
DOI:10.1055/s-0033-1339113