Technology Process of [{(4,4-dibromo-2,2-dimethylbut-3-en-1-yl)oxy}methyl]benzene
There total 4 articles about [{(4,4-dibromo-2,2-dimethylbut-3-en-1-yl)oxy}methyl]benzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
carbon tetrabromide;
With
triphenylphosphine;
In
dichloromethane;
at 0 ℃;
for 0.666667h;
Inert atmosphere;
3-benzyloxypivalic aldehyde;
In
dichloromethane;
at 0 - 20 ℃;
Inert atmosphere;
DOI:10.1021/jo301817w
DOI:10.1021/jo301817w
- Guidance literature:
-
Multi-step reaction with 3 steps
1: tetra-(n-butyl)ammonium iodide; potassium hydroxide / toluene; water / 25 - 30 °C
2: sodium hypochlorite; sodium hydrogencarbonate; potassium bromide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / water; dichloromethane / 3.5 h / -10 - 30 °C
3: triphenylphosphine / dichloromethane / 0 - 30 °C
With
sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; tetra-(n-butyl)ammonium iodide; sodium hydrogencarbonate; triphenylphosphine; potassium bromide; potassium hydroxide;
In
dichloromethane; water; toluene;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium hypochlorite; sodium hydrogencarbonate; potassium bromide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / water; dichloromethane / 3.5 h / -10 - 30 °C
2: triphenylphosphine / dichloromethane / 0 - 30 °C
With
sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate; triphenylphosphine; potassium bromide;
In
dichloromethane; water;
