(R*,R*)-(+/-)-1,2-phenylenebis(methylphenylphosphine)

Base Information

• Chemical Name: (R*,R*)-(+/-)-1,2-phenylenebis(methylphenylphosphine)
• CAS No.: 122331-49-1
• Molecular Formula: C₂₀H₂₀P₂
• Molecular Weight: 322.326
• Mol file: 122331-49-1.mol

Synonyms:(R*,R*)-(+/-)-1,2-phenylenebis(methylphenylphosphine)

Chemical Property of (R*,R*)-(+/-)-1,2-phenylenebis(methylphenylphosphine)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R*,R*)-(+/-)-1,2-phenylenebis(methylphenylphosphine)

There total 2 articles about (R*,R*)-(+/-)-1,2-phenylenebis(methylphenylphosphine) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,2-diphenylphosphinobenzene (38023-29-9) + methyl iodide (74-88-4) → (RS)-o-phenylenebis(methylphenylphosphine) (72091-01-1,72091-02-2,72150-36-8,72150-63-1,77410-05-0) + (R*,R*)-(+/-)-1,2-phenylenebis(methylphenylphosphine) (72091-01-1,72091-02-2,72150-36-8,72150-63-1,77410-05-0,122331-49-1)

Guidance literature:

With n-butyllithium; Yield given. Multistep reaction. Title compound not separated from byproducts; 1) THF, hexane, -78 deg C; 2) -78 deg C --> room temperature;

DOI:10.1021/ja00403a041

Reference yield:

→ (R*,R*)-(+/-)-1,2-phenylenebis(methylphenylphosphine) (72091-01-1,72091-02-2,72150-36-8,72150-63-1,77410-05-0,122331-49-1)

Guidance literature:

Na, H2O;

DOI:10.1021/ja00515a016

Reference yield: 94.0%

ammonium hexafluorophosphate + (R*,R*)-(+/-)-1,2-phenylenebis(methylphenylphosphine) (122331-49-1) + {T-4-(R(*),S(*))}-dicarbonyl{1,2-phenylenebis(methylphenylphosphine)}nickel(0) (87760-26-7,77029-28-8) → rac-chloro((RS)-o-phenylenebis(methylphenylphosphine))((RR,SS)-o-phenylenebis(methylphenylphosphine))nickel(II)hexafluorophosphate (77059-67-7)

Guidance literature:

With sulfuryl dichloride; In ethanol; dichloromethane; water; byproducts: CO, SO2; dicarbinyl dissolved in dichloromethane and soln. treated with SO2Cl2 in dichloromethane at 0°C under N2 atm., after 20 min (RR,SS)-diphos added, solvent removed and residue dissolved in ethanol, NH4PF6 in water added; ppt. washed and dried and recrystd. from dichloromethane by addn. diethyl ether; elem. anal.;

upstream raw materials:

1,2-diphenylphosphinobenzene

methyl iodide

Downstream raw materials:

(R*,R*)-(+/-)-(acetonitrile)(η5-cyclopentadienyl){1,2-phenylenebis(methylphenylphosphine)}iron(II) hexafluorophosphate

meso-((RR)-o-phenylenebis(methylphenylphosphine))((SS)-o-phenylenebis(methylphenylphosphine))nickel(II) hexafluorophosphate

rac-bis((RR,SS)-o-phenylenebis(methylphenylphosphine))nickel(II) hexafluorophosphate

rac-chloro((RS)-o-phenylenebis(methylphenylphosphine))((RR,SS)-o-phenylenebis(methylphenylphosphine))nickel(II)hexafluorophosphate