6-(2-Fluoropyridin-3-Yl)-9-(Tetrahydro-2H-Pyran-2-Yl)-9H-Purine

Base Information

Chemical Name:6-(2-Fluoropyridin-3-Yl)-9-(Tetrahydro-2H-Pyran-2-Yl)-9H-Purine
CAS No.:1093101-52-0
Molecular Formula:C₁₅H₁₄FN₅O
Molecular Weight:299.307
Hs Code.:2933998090
Mol file:1093101-52-0.mol

Synonyms:6-(2-fluoropyridin-3-yl)-9-(tetrahydro-2-hydro-pyran-2-yl)-9H-purine

Suppliers and Price of 6-(2-Fluoropyridin-3-Yl)-9-(Tetrahydro-2H-Pyran-2-Yl)-9H-Purine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-(2-Fluoropyridin-3-yl)-9-(oxan-2-yl)purine
2.5mg
$ 45.00

Matrix Scientific
6-(2-Fluoropyridin-3-yl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purine 95%
2.500g
$ 1816.00

Crysdot
6-(2-Fluoropyridin-3-yl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purine 95+%
1g
$ 740.00

Chemenu
6-(2-Fluoropyridin-3-yl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purine 95%
1g
$ 1057.00

Apolloscientific
6-(2-Fluoropyridin-3-yl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purine
250mg
$ 103.00

Ambeed
6-(2-Fluoropyridin-3-yl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purine 95+%
250mg
$ 58.00

Ambeed
6-(2-Fluoropyridin-3-yl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purine 95+%
100mg
$ 39.00

Ambeed
6-(2-Fluoropyridin-3-yl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purine 95+%
1g
$ 135.00

Alichem
6-(2-Fluoropyridin-3-yl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purine
1g
$ 1187.55

Alichem
6-(2-Fluoropyridin-3-yl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purine
250mg
$ 452.00

Total 9 raw suppliers

Chemical Property of 6-(2-Fluoropyridin-3-Yl)-9-(Tetrahydro-2H-Pyran-2-Yl)-9H-Purine

Chemical Property:

Boiling Point:532.8±60.0 °C(Predicted)
PKA:1.25±0.10(Predicted)
Density:1.50±0.1 g/cm3(Predicted)
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

6-(2-Fluoropyridin-3-yl)-9-(oxan-2-yl)purine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6-(2-Fluoropyridin-3-Yl)-9-(Tetrahydro-2H-Pyran-2-Yl)-9H-Purine

There total 6 articles about 6-(2-Fluoropyridin-3-Yl)-9-(Tetrahydro-2H-Pyran-2-Yl)-9H-Purine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 7306-68-5
6-chloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purine

: 174669-73-9
(2-fluoro-pyridin-3-yl)boronic acid

: 1093101-52-0
6-(2-fluoropyridin-3-yl)-9-(tetrahydro-2-hydro-pyran-2-yl)-9H-purine

Guidance literature:: With bis(di-tert-?butyl(4-?dimethylaminophenyl)?phosphine)?dichloropalladium(II); potassium acetate; In ethanol; water; at 80 ℃; for 2h; Inert atmosphere;
DOI:10.1021/jm901081g

Reference yield: 74.0%

: 7306-68-5
6-chloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purine

: 452972-14-4
2-[3-(2-fluoro)pyridine]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 1093101-52-0
6-(2-fluoropyridin-3-yl)-9-(tetrahydro-2-hydro-pyran-2-yl)-9H-purine

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate; In 1,4-dioxane; water; at 100 ℃; for 3h; Inert atmosphere;

Reference yield:

: 110-87-2
3,4-dihydro-2H-pyran

: 1093101-52-0
6-(2-fluoropyridin-3-yl)-9-(tetrahydro-2-hydro-pyran-2-yl)-9H-purine

Guidance literature:: Multi-step reaction with 2 steps

1: toluene-4-sulfonic acid / ethyl acetate / 2 h / Reflux

2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate / 1,4-dioxane; water / 3 h / 100 °C / Inert atmosphere

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate; toluene-4-sulfonic acid; In 1,4-dioxane; water; ethyl acetate;