5-((4-chlorophenyl)(4-methoxyphenyl)methyl)-2,2-dimethyl-1,3-dioxane-4,6-dione

Base Information

Chemical Name:5-((4-chlorophenyl)(4-methoxyphenyl)methyl)-2,2-dimethyl-1,3-dioxane-4,6-dione
CAS No.:1381982-89-3
Molecular Formula:C₂₀H₁₉ClO₅
Molecular Weight:374.821
Hs Code.:

Synonyms:5-((4-chlorophenyl)(4-methoxyphenyl)methyl)-2,2-dimethyl-1,3-dioxane-4,6-dione

Suppliers and Price of 5-((4-chlorophenyl)(4-methoxyphenyl)methyl)-2,2-dimethyl-1,3-dioxane-4,6-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-((4-chlorophenyl)(4-methoxyphenyl)methyl)-2,2-dimethyl-1,3-dioxane-4,6-dione

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-((4-chlorophenyl)(4-methoxyphenyl)methyl)-2,2-dimethyl-1,3-dioxane-4,6-dione

There total 4 articles about 5-((4-chlorophenyl)(4-methoxyphenyl)methyl)-2,2-dimethyl-1,3-dioxane-4,6-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 15795-54-7
5-(4-methoxybenzylidene)-2,2-dimethyl-[1,3]dioxane-4,6-dione

: 1679-18-1
4-Chlorophenylboronic acid

: 1381982-89-3
5-((4-chlorophenyl)(4-methoxyphenyl)methyl)-2,2-dimethyl-1,3-dioxane-4,6-dione

Guidance literature:: 4-Chlorophenylboronic acid; With diethylzinc; In toluene; at 20 ℃; for 4h; Inert atmosphere;

5-(4-methoxybenzylidene)-2,2-dimethyl-[1,3]dioxane-4,6-dione; In tetrahydrofuran; toluene; at 20 ℃; for 4h;
DOI:10.1016/j.tet.2020.130967

Reference yield: 53.0%

: 15795-54-7
5-(4-methoxybenzylidene)-2,2-dimethyl-[1,3]dioxane-4,6-dione

: 873-77-8
(4-chlorphenyl)magnesium bromide

: 1381982-89-3
5-((4-chlorophenyl)(4-methoxyphenyl)methyl)-2,2-dimethyl-1,3-dioxane-4,6-dione

Guidance literature:: In tetrahydrofuran; diethyl ether; at 0 - 20 ℃; for 21h; Inert atmosphere;
DOI:10.1021/ol301442z

Reference yield:

: 2033-24-1
cycl-isopropylidene malonate

: 1381982-89-3
5-((4-chlorophenyl)(4-methoxyphenyl)methyl)-2,2-dimethyl-1,3-dioxane-4,6-dione

Guidance literature:: Multi-step reaction with 2 steps

1: piperidine; acetic acid / benzene

2: tetrahydrofuran; diethyl ether / 21 h / 0 - 20 °C / Inert atmosphere

With piperidine; acetic acid; In tetrahydrofuran; diethyl ether; benzene;
DOI:10.1021/ol301442z