3-bromo-2-(4-chloro-3-trifluoromethylphenoxy)-6-methyl-5-nitropyridine

Base Information

Chemical Name:3-bromo-2-(4-chloro-3-trifluoromethylphenoxy)-6-methyl-5-nitropyridine
CAS No.:1049707-75-6
Molecular Formula:C₁₃H₇BrClF₃N₂O₃
Molecular Weight:411.562
Hs Code.:

Synonyms:3-bromo-2-(4-chloro-3-trifluoromethylphenoxy)-6-methyl-5-nitropyridine

Suppliers and Price of 3-bromo-2-(4-chloro-3-trifluoromethylphenoxy)-6-methyl-5-nitropyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-bromo-2-(4-chloro-3-trifluoromethylphenoxy)-6-methyl-5-nitropyridine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-bromo-2-(4-chloro-3-trifluoromethylphenoxy)-6-methyl-5-nitropyridine

There total 5 articles about 3-bromo-2-(4-chloro-3-trifluoromethylphenoxy)-6-methyl-5-nitropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 856834-95-2
3-bromo-2-chloro-6-methyl-5-nitropyridine

: 6294-93-5
4-chloro-3-trifluoromethylphenol

: 1049707-75-6
3-bromo-2-(4-chloro-3-trifluoromethylphenoxy)-6-methyl-5-nitropyridine

Guidance literature:: 4-chloro-3-trifluoromethylphenol; With sodium hydride; 1,1,1,3,3,3-hexamethyl-disilazane; In 1,4-dioxane; at 20 ℃; for 0.5h;

3-bromo-2-chloro-6-methyl-5-nitropyridine; In 1,4-dioxane; at 20 ℃; for 22h;

Reference yield:

: 3279-76-3,91914-07-7
6-hydroxy-2-methylpyridine

: 1049707-75-6
3-bromo-2-(4-chloro-3-trifluoromethylphenoxy)-6-methyl-5-nitropyridine

Guidance literature:: Multi-step reaction with 5 steps

1.1: N-Bromosuccinimide / acetonitrile / 2.17 h / 0 - 29 °C

2.1: n-butyllithium / tetrahydrofuran; hexane / 3.5 h / -80 - -74 °C / Cooling with ether-dry ice

2.2: -78 - 20 °C

3.1: nitric acid / water / 3.5 h / 0 - 20 °C

3.2: pH 4

4.1: trichlorophosphate / 7 h / Heating / reflux

5.1: sodium hydride; 1,1,1,3,3,3-hexamethyl-disilazane / 1,4-dioxane / 0.5 h / 20 °C

5.2: 22 h / 20 °C

With N-Bromosuccinimide; n-butyllithium; nitric acid; sodium hydride; 1,1,1,3,3,3-hexamethyl-disilazane; trichlorophosphate; In tetrahydrofuran; 1,4-dioxane; hexane; water; acetonitrile;

Reference yield:

: 500587-45-1
3,5-dibromo-2-hydroxy-6-methylpyridine

: 1049707-75-6
3-bromo-2-(4-chloro-3-trifluoromethylphenoxy)-6-methyl-5-nitropyridine

Guidance literature:: Multi-step reaction with 4 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 3.5 h / -80 - -74 °C / Cooling with ether-dry ice

1.2: -78 - 20 °C

2.1: nitric acid / water / 3.5 h / 0 - 20 °C

2.2: pH 4

3.1: trichlorophosphate / 7 h / Heating / reflux

4.1: sodium hydride; 1,1,1,3,3,3-hexamethyl-disilazane / 1,4-dioxane / 0.5 h / 20 °C

4.2: 22 h / 20 °C

With n-butyllithium; nitric acid; sodium hydride; 1,1,1,3,3,3-hexamethyl-disilazane; trichlorophosphate; In tetrahydrofuran; 1,4-dioxane; hexane; water;