[1-(Phenylsulfonyl)-1H-indol-2-yl]methanol

Base Information

Chemical Name:[1-(Phenylsulfonyl)-1H-indol-2-yl]methanol
CAS No.:73282-11-8
Molecular Formula:C15H13 N O3 S
Molecular Weight:287.339
Hs Code.:
DSSTox Substance ID:DTXSID00379905
Nikkaji Number:J702.009K
Wikidata:Q82169932
Mol file:73282-11-8.mol

Synonyms:73282-11-8;[1-(Phenylsulfonyl)-1H-indol-2-yl]methanol;(1-(phenylsulfonyl)-1H-indol-2-yl)methanol;[1-(benzenesulfonyl)indol-2-yl]methanol;[1-(Benzenesulfonyl)-1H-indol-2-yl]methanol;Oprea1_111003;DTXSID00379905;MFCD03086093;1-(Phenylsulfonyl)-1H-indole-2-methanol;MS-22146;FT-0605386;[1-(PHENYLSULFONYL-1H-INDOL-2-YL]METHANOL;J-502696;[1-(Phenylsulfonyl)-1H-indol-2-yl]methanol, AldrichCPR

Suppliers and Price of [1-(Phenylsulfonyl)-1H-indol-2-yl]methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
[1-(PHENYLSULFONYL)-1H-INDOL-2-YL]METHANOL 95.00%
1G
$ 750.70

Total 9 raw suppliers

Chemical Property of [1-(Phenylsulfonyl)-1H-indol-2-yl]methanol

Chemical Property:

Vapor Pressure:4.84E-12mmHg at 25°C
Melting Point:76℃
Boiling Point:529.5°C at 760 mmHg
Flash Point:274°C
PSA：67.68000
Density:1.32g/cm³
LogP:3.45140
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:287.06161445
Heavy Atom Count:20
Complexity:425

Purity/Quality:

98%min ^*data from raw suppliers

[1-(PHENYLSULFONYL)-1H-INDOL-2-YL]METHANOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s): R36/37/38:Irritating to eyes, respiratory system and skin.;
Hazard Codes:Xn
Statements: 36/37/38-22
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)S(=O)(=O)N2C3=CC=CC=C3C=C2CO

Technology Process of [1-(Phenylsulfonyl)-1H-indol-2-yl]methanol

There total 4 articles about [1-(Phenylsulfonyl)-1H-indol-2-yl]methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 99275-44-2
2-iodo-1-(phenylsulfonyl)-1H-indole

: 73282-11-8
<1-(phenylsulfonyl)indol-2-yl>methanol

Guidance literature:: With ethylmagnesium bromide; In tetrahydrofuran; 1.) 0 deg C, 30 min, r.t., 30 min; 2.) r.t., overnight;
DOI:10.3987/com-95-s31

Reference yield:

: 80360-23-2
1-(phenylsulfonyl)-1H-indole-2-carbaldehyde

: 73282-11-8
<1-(phenylsulfonyl)indol-2-yl>methanol

Guidance literature:: With diisobutylaluminium hydride; In tetrahydrofuran; hexane; at -78 ℃; for 1h;
DOI:10.1021/jm020901d

Reference yield:

: 40899-71-6
1-benzenesulfonylindole

: 73282-11-8
<1-(phenylsulfonyl)indol-2-yl>methanol

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-BuLi / tetrahydrofuran / 1 h / -78 °C

1.2: tetrahydrofuran / 2 h / -78 °C

2.1: DIBAL-H / tetrahydrofuran; hexane / 1 h / -78 °C

With n-butyllithium; diisobutylaluminium hydride; In tetrahydrofuran; hexane;
DOI:10.1021/jm020901d