1-tert-butylacetyl-4-(3'-p-toluenesulfonamido-4',6'-di-O-acetyl-2',3'-dideoxy-α-D-allopyranosyloxymethyl)-1H-1,2,3-triazol

Base Information

Chemical Name:1-tert-butylacetyl-4-(3'-p-toluenesulfonamido-4',6'-di-O-acetyl-2',3'-dideoxy-α-D-allopyranosyloxymethyl)-1H-1,2,3-triazol
CAS No.:1644077-53-1
Molecular Formula:C₂₆H₃₆N₄O₁₀S
Molecular Weight:596.659
Hs Code.:

Synonyms:1-tert-butylacetyl-4-(3'-p-toluenesulfonamido-4',6'-di-O-acetyl-2',3'-dideoxy-α-D-allopyranosyloxymethyl)-1H-1,2,3-triazol

Suppliers and Price of 1-tert-butylacetyl-4-(3'-p-toluenesulfonamido-4',6'-di-O-acetyl-2',3'-dideoxy-α-D-allopyranosyloxymethyl)-1H-1,2,3-triazol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-tert-butylacetyl-4-(3'-p-toluenesulfonamido-4',6'-di-O-acetyl-2',3'-dideoxy-α-D-allopyranosyloxymethyl)-1H-1,2,3-triazol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-tert-butylacetyl-4-(3'-p-toluenesulfonamido-4',6'-di-O-acetyl-2',3'-dideoxy-α-D-allopyranosyloxymethyl)-1H-1,2,3-triazol

There total 4 articles about 1-tert-butylacetyl-4-(3'-p-toluenesulfonamido-4',6'-di-O-acetyl-2',3'-dideoxy-α-D-allopyranosyloxymethyl)-1H-1,2,3-triazol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 6367-36-8
tert-butyl 2-azidoacetate

propargyl 3-(p-toluenesulfonamido)-4,6-di-O-acetyl-2,3-dideoxy-α-D-allohexopyranoside: 1310060-46-8
propargyl 3-(p-toluenesulfonamido)-4,6-di-O-acetyl-2,3-dideoxy-α-D-allohexopyranoside

: 1644077-53-1
1-tert-butylacetyl-4-(3'-p-toluenesulfonamido-4',6'-di-O-acetyl-2',3'-dideoxy-α-D-allopyranosyloxymethyl)-1H-1,2,3-triazol

Guidance literature:: With copper(ll) sulfate pentahydrate; sodium L-ascorbate; In N,N-dimethyl-formamide; at 70 ℃; for 0.25h; regioselective reaction; Sealed tube; Microwave irradiation;
DOI:10.3762/bjoc.10.134

Reference yield:

: 70-55-3
toluene-4-sulfonamide

: 1644077-53-1
1-tert-butylacetyl-4-(3'-p-toluenesulfonamido-4',6'-di-O-acetyl-2',3'-dideoxy-α-D-allopyranosyloxymethyl)-1H-1,2,3-triazol

Guidance literature:: Multi-step reaction with 2 steps

1: boron trifluoride diethyl etherate / 1,2-dichloro-ethane / 0.33 h / 20 °C / Inert atmosphere

2: copper(ll) sulfate pentahydrate; sodium L-ascorbate / N,N-dimethyl-formamide / 0.25 h / 70 °C / Sealed tube; Microwave irradiation

With copper(ll) sulfate pentahydrate; boron trifluoride diethyl etherate; sodium L-ascorbate; In 1,2-dichloro-ethane; N,N-dimethyl-formamide; 2: |Huisgen Cycloaddition;
DOI:10.3762/bjoc.10.134

Reference yield:

: 2873-29-2
D-glucal triacetate

: 1644077-53-1
1-tert-butylacetyl-4-(3'-p-toluenesulfonamido-4',6'-di-O-acetyl-2',3'-dideoxy-α-D-allopyranosyloxymethyl)-1H-1,2,3-triazol

Guidance literature:: Multi-step reaction with 2 steps

1: boron trifluoride diethyl etherate / 1,2-dichloro-ethane / 0.33 h / 20 °C / Inert atmosphere

2: copper(ll) sulfate pentahydrate; sodium L-ascorbate / N,N-dimethyl-formamide / 0.25 h / 70 °C / Sealed tube; Microwave irradiation

With copper(ll) sulfate pentahydrate; boron trifluoride diethyl etherate; sodium L-ascorbate; In 1,2-dichloro-ethane; N,N-dimethyl-formamide; 2: |Huisgen Cycloaddition;
DOI:10.3762/bjoc.10.134