(R)-3-chlorophenylalanine methyl ester hydrochloride

Base Information

Chemical Name:(R)-3-chlorophenylalanine methyl ester hydrochloride
CAS No.:457654-75-0
Molecular Formula:C₁₀H₁₂ClNO₂*ClH
Molecular Weight:250.125
Hs Code.:

Synonyms:(R)-3-chlorophenylalanine methyl ester hydrochloride

Suppliers and Price of (R)-3-chlorophenylalanine methyl ester hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Acrotein
3-Chloro-D-phenylalaninemethylesterHCl 97%
1g
$ 247.50

Acrotein
3-Chloro-D-phenylalaninemethylesterHCl 97%
0.5g
$ 165.00

Total 5 raw suppliers

Chemical Property of (R)-3-chlorophenylalanine methyl ester hydrochloride

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

3-Chloro-D-phenylalaninemethylesterHCl 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-3-chlorophenylalanine methyl ester hydrochloride

There total 1 articles about (R)-3-chlorophenylalanine methyl ester hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 67-56-1
methanol

: 80126-52-9
(R)-2-amino-3-(3-chlorophenyl)propanoic acid

: 457654-75-0
(R)-3-chlorophenylalanine methyl ester hydrochloride

Guidance literature:: methanol; With acetyl chloride; at 0 ℃; for 0.25h;

(R)-2-amino-3-(3-chlorophenyl)propanoic acid; for 38h; Reflux;
DOI:10.1016/j.tet.2014.04.045

Reference yield:

: 457654-75-0
(R)-3-chlorophenylalanine methyl ester hydrochloride

: 79-04-9
chloroacetyl chloride

: 1610691-83-2
(R)-N-(2-chloroacetyl)-3-chlorophenylalanine methyl ester

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 1h;
DOI:10.1016/j.tet.2014.04.045

Reference yield:

: 457654-75-0
(R)-3-chlorophenylalanine methyl ester hydrochloride

: 1610691-88-7
(R)-N-[N-(2,2-dimethoxyethyl)glycinyl]-3-chlorophenylalanine methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 1 h / 0 - 20 °C

2: sodium iodide / dichloromethane / 48 h / 20 °C

With triethylamine; sodium iodide; In dichloromethane;
DOI:10.1016/j.tet.2014.04.045