methyl 2,3-di-O-benzoyl-5-O-(p-tolylsulphonyl)-α-D-arabinofuranoside

Base Information

• Chemical Name: methyl 2,3-di-O-benzoyl-5-O-(p-tolylsulphonyl)-α-D-arabinofuranoside
• CAS No.: 94411-12-8
• Molecular Formula: C₂₇H₂₆O₉S
• Molecular Weight: 526.564
• Mol file: 94411-12-8.mol

Synonyms:methyl 2,3-di-O-benzoyl-5-O-(p-tolylsulphonyl)-α-D-arabinofuranoside

Chemical Property of methyl 2,3-di-O-benzoyl-5-O-(p-tolylsulphonyl)-α-D-arabinofuranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2,3-di-O-benzoyl-5-O-(p-tolylsulphonyl)-α-D-arabinofuranoside

There total 3 articles about methyl 2,3-di-O-benzoyl-5-O-(p-tolylsulphonyl)-α-D-arabinofuranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzoyl chloride (98-88-4) + methyl 5-O-p-tosyl-D-arabinofuranoside (50600-50-5) → methyl 2,3-di-O-benzoyl-5-O-(p-tolylsulphonyl)-α-D-arabinofuranoside (94411-12-8)

Guidance literature:

With pyridine; at 0 - 20 ℃; for 24h;

DOI:10.1134/S1070428019040158

Reference yield:

D-arabinofuranose (532-20-7,613-83-2,7261-25-8,7687-39-0,13221-22-2,14795-83-6,15761-67-8,20074-49-1,25545-03-3,25545-04-4,32445-75-3,34436-17-4,36441-93-7,36468-53-8,37110-85-3,37388-49-1,38029-69-5,40461-77-6,40461-89-0,41546-19-4,41546-20-7,41546-21-8,41546-26-3,41546-29-6,41546-30-9,41546-31-0,126872-16-0,131064-98-7) → methyl 2,3-di-O-benzoyl-5-O-(p-tolylsulphonyl)-α-D-arabinofuranoside (94411-12-8)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrogenchloride / 24 h / 0 - 20 °C

2: pyridine / 24 h / 0 - 20 °C

3: pyridine / 24 h / 0 - 20 °C

With pyridine; hydrogenchloride;

DOI:10.1134/S1070428019040158

Reference yield:

methanol (67-56-1) + D-Arabinose (10323-20-3) + benzoyl chloride (98-88-4) + p-toluenesulfonyl chloride (98-59-9) → methyl 2,3-di-O-benzoyl-5-O-(p-tolylsulphonyl)-α-D-arabinofuranoside (94411-12-8)

Guidance literature:

With pyridine; hydrogenchloride; Yield given. Multistep reaction; 1.) 35 deg C, 3 h, 2.) dichloromethane, 64 h (4 deg C), 7 h (20 deg C), 3.) 20 deg C, overnight;

upstream raw materials:

methanol

D-Arabinose

benzoyl chloride

p-toluenesulfonyl chloride

Downstream raw materials:

methyl 2,3-di-O-benzoyl-5-deoxy-5-iodo-α-D-arabinofuranoside

2,3-di-O-benzoyl-5-deoxy-D-threo-pentos-4-ulose

methyl 2,3-di-O-benzoyl-5-deoxy-α-D-threo-pent-4-enofuranoside

C₂₃H₂₄O₄S₄