6-TRITYL-1,2,3,4-TETRA-O-ACETYL-BETA-D-GLUCOSE

Base Information

• Chemical Name: 6-TRITYL-1,2,3,4-TETRA-O-ACETYL-BETA-D-GLUCOSE
• CAS No.: 37074-90-1
• Molecular Formula: C33H34O10
• Molecular Weight: 590.627
• Mol file: 37074-90-1.mol

Synonyms:b-D-Glucopyranose,6-O-(triphenylmethyl)-, tetraacetate (9CI);1,2,3,4-Tetra-O-acetyl-6-O-triphenylmethyl-b-D-glucopyranose;NSC 404268;

Chemical Property of 6-TRITYL-1,2,3,4-TETRA-O-ACETYL-BETA-D-GLUCOSE

Chemical Property:

• Melting Point: 165-166 °C
• Boiling Point: 633.3 °C at 760 mmHg
• Flash Point: 262.6 °C
• PSA: 134.66000
• Density: 1.28 g/cm³
• LogP: 3.46500

Purity/Quality:

97% ^*data from raw suppliers

1,2,3,4-Tetra-O-acetyl-6-O-trityl-b-D-glucopyranose ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-TRITYL-1,2,3,4-TETRA-O-ACETYL-BETA-D-GLUCOSE

There total 15 articles about 6-TRITYL-1,2,3,4-TETRA-O-ACETYL-BETA-D-GLUCOSE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

acetic anhydride (108-24-7) + 6-O-trityl-D-glucopyranose (54325-28-9) → 1,2,3,4-tetra-O-acetyl-6-O-trityl-β-D-glucopyranose (37074-90-1)

Guidance literature:

With dmap; at 20 ℃; Large scale;

Reference yield: 41.0%

alpha-D-glucopyranose (492-62-6) + acetic anhydride (108-24-7) + trityl chloride (76-83-5) → 1,2,3,4-tetra-O-acetyl-6-O-triphenylmethyl-α-D-glucopyranose (10028-44-1) + 1,2,3,4-tetra-O-acetyl-6-O-trityl-β-D-glucopyranose (37074-90-1)

Guidance literature:

With pyridine; at 80 - 100 ℃; Cooling;

Reference yield: 40.4%

D-Glucose (2280-44-6) + acetic anhydride (108-24-7) + trityl chloride (76-83-5) → 1,2,3,4-tetra-O-acetyl-6-O-trityl-β-D-glucopyranose (37074-90-1)

Guidance literature:

D-Glucose; trityl chloride; With pyridine; at 20 ℃; for 24h;

acetic anhydride; for 6.5h;

upstream raw materials:

D-glucose

bromo-triphenyl-methane

trityl chloride

6-O-trityl-α-D-glucose

Downstream raw materials:

2,3,4-tri-O-acetyllevoglucosan

1,2,3,4-tetra-O-acetyl-β-D-glucopyranose

β-D-gentiobiose octaacetate

1,2,3,4-tetra-O-acetyl-6-O-(2,3,5-tri-O-benzoyl-α-L-arabinofuranosyl)-β-D-glucopyranose