2-(2-(2-nitro-5-chlorophenyl)hydrazono)propionic acid ethyl ester

Base Information

• Chemical Name: 2-(2-(2-nitro-5-chlorophenyl)hydrazono)propionic acid ethyl ester
• CAS No.: 1579994-92-5
• Molecular Formula: C₁₁H₁₂ClN₃O₄
• Molecular Weight: 285.687
• Mol file: 1579994-92-5.mol

Synonyms:2-(2-(2-nitro-5-chlorophenyl)hydrazono)propionic acid ethyl ester

Chemical Property of 2-(2-(2-nitro-5-chlorophenyl)hydrazono)propionic acid ethyl ester

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 2-(2-(2-nitro-5-chlorophenyl)hydrazono)propionic acid ethyl ester

There total 4 articles about 2-(2-(2-nitro-5-chlorophenyl)hydrazono)propionic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

2-oxo-propionic acid ethyl ester (617-35-6) + (5-chloro-2-nitrophenyl)hydrazine hydrochloride → 2-(2-(2-nitro-5-chlorophenyl)hydrazono)propionic acid ethyl ester (1579994-92-5)

Guidance literature:

In ethanol; at 20 ℃; for 0.0833333h;

DOI:10.1016/j.bmc.2014.01.047

Reference yield: 37.0%

ethanol (64-17-5) + ethyl acetate (141-78-6) + (5-chloro-2-nitrophenyl)hydrazine hydrochloride → 2-(2-(2-nitro-5-chlorophenyl)hydrazono)propionic acid ethyl ester (1579994-92-5)

Guidance literature:

In ethanol; at 20 ℃; for 1h;

DOI:10.1016/j.ejmech.2019.111985

Reference yield: 36.8%

2-oxo-propionic acid ethyl ester (617-35-6) + methanol (67-56-1) + (5-chloro-2-nitrophenyl)hydrazine hydrochloride → 2-(2-(2-nitro-5-chlorophenyl)hydrazono)propionic acid ethyl ester (1579994-92-5)

Guidance literature:

at 20 ℃; for 0.0833333h;

upstream raw materials:

2-oxo-propionic acid ethyl ester

5-chloro-2-nitroaniline

methanol

ethanol

Downstream raw materials:

4-((4-trifluoromethylphenyl)amino)-7-nitro-1H-indole-2-carboxylic acid ethyl ester