4-(3-((2,5-dioxopyrrolidin-1-yl)oxy)-3-oxopropyl)-2,6-di-isopropylphenyl 7-(4-(((((9H-fluoren-9-yl)methoxy)carbonyl)-amino)methyl)-1H-1,2,3-triazol-1-yl)-4-oxoheptanoate

Base Information

Chemical Name:4-(3-((2,5-dioxopyrrolidin-1-yl)oxy)-3-oxopropyl)-2,6-di-isopropylphenyl 7-(4-(((((9H-fluoren-9-yl)methoxy)carbonyl)-amino)methyl)-1H-1,2,3-triazol-1-yl)-4-oxoheptanoate
CAS No.:1357309-74-0
Molecular Formula:C₄₄H₄₉N₅O₉
Molecular Weight:791.901
Hs Code.:

4-(3-((2,5-dioxopyrrolidin-1-yl)oxy)-3-oxopropyl)-2,6-di-isopropylphenyl 7-(4-(((((9H-fluoren-9-yl)methoxy)carbonyl)-amino)methyl)-1H-1,2,3-triazol-1-yl)-4-oxoheptanoate

Synonyms:4-(3-((2,5-dioxopyrrolidin-1-yl)oxy)-3-oxopropyl)-2,6-di-isopropylphenyl 7-(4-(((((9H-fluoren-9-yl)methoxy)carbonyl)-amino)methyl)-1H-1,2,3-triazol-1-yl)-4-oxoheptanoate

Suppliers and Price of 4-(3-((2,5-dioxopyrrolidin-1-yl)oxy)-3-oxopropyl)-2,6-di-isopropylphenyl 7-(4-(((((9H-fluoren-9-yl)methoxy)carbonyl)-amino)methyl)-1H-1,2,3-triazol-1-yl)-4-oxoheptanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-(3-((2,5-dioxopyrrolidin-1-yl)oxy)-3-oxopropyl)-2,6-di-isopropylphenyl 7-(4-(((((9H-fluoren-9-yl)methoxy)carbonyl)-amino)methyl)-1H-1,2,3-triazol-1-yl)-4-oxoheptanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(3-((2,5-dioxopyrrolidin-1-yl)oxy)-3-oxopropyl)-2,6-di-isopropylphenyl 7-(4-(((((9H-fluoren-9-yl)methoxy)carbonyl)-amino)methyl)-1H-1,2,3-triazol-1-yl)-4-oxoheptanoate

There total 4 articles about 4-(3-((2,5-dioxopyrrolidin-1-yl)oxy)-3-oxopropyl)-2,6-di-isopropylphenyl 7-(4-(((((9H-fluoren-9-yl)methoxy)carbonyl)-amino)methyl)-1H-1,2,3-triazol-1-yl)-4-oxoheptanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6066-82-6
1-hydroxy-pyrrolidine-2,5-dione

: 1357309-73-9
C₄₀H₄₆N₄O₇

: 1357309-74-0
4-(3-((2,5-dioxopyrrolidin-1-yl)oxy)-3-oxopropyl)-2,6-di-isopropylphenyl 7-(4-(((((9H-fluoren-9-yl)methoxy)carbonyl)-amino)methyl)-1H-1,2,3-triazol-1-yl)-4-oxoheptanoate

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; for 40h; Inert atmosphere;
DOI:10.1016/j.bmc.2011.07.049

Reference yield:

: 127896-08-6
Fmoc-N-propargylamine

: 1357309-74-0
4-(3-((2,5-dioxopyrrolidin-1-yl)oxy)-3-oxopropyl)-2,6-di-isopropylphenyl 7-(4-(((((9H-fluoren-9-yl)methoxy)carbonyl)-amino)methyl)-1H-1,2,3-triazol-1-yl)-4-oxoheptanoate

Guidance literature:: Multi-step reaction with 3 steps

1: copper(II) sulfate; sodium L-ascorbate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine / water; tert-butyl alcohol / 16 h / 20 °C / Inert atmosphere

2: trifluoroacetic acid / dichloromethane / 1 h / Inert atmosphere

3: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 40 h / Inert atmosphere

With copper(II) sulfate; sodium L-ascorbate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic acid; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine; In dichloromethane; water; tert-butyl alcohol;
DOI:10.1016/j.bmc.2011.07.049

Reference yield:

: 1254943-32-2
4-(3-(tert-butoxy)-3-oxopropyl)-2,6-diisopropylphenyl 7-azido-4-oxoheptanoate

: 1357309-74-0
4-(3-((2,5-dioxopyrrolidin-1-yl)oxy)-3-oxopropyl)-2,6-di-isopropylphenyl 7-(4-(((((9H-fluoren-9-yl)methoxy)carbonyl)-amino)methyl)-1H-1,2,3-triazol-1-yl)-4-oxoheptanoate

Guidance literature:: Multi-step reaction with 3 steps

1: copper(II) sulfate; sodium L-ascorbate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine / water; tert-butyl alcohol / 16 h / 20 °C / Inert atmosphere

2: trifluoroacetic acid / dichloromethane / 1 h / Inert atmosphere

3: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 40 h / Inert atmosphere

With copper(II) sulfate; sodium L-ascorbate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic acid; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine; In dichloromethane; water; tert-butyl alcohol;
DOI:10.1016/j.bmc.2011.07.049