1-(3'-amino-4'-methoxyphenyl)-1-(3'',4'',5''-trimethoxyphenyl)ethylene

Base Information

• Chemical Name: 1-(3'-amino-4'-methoxyphenyl)-1-(3'',4'',5''-trimethoxyphenyl)ethylene
• CAS No.: 1070195-62-8
• Molecular Formula: C₁₈H₂₁NO₄
• Molecular Weight: 315.369
• Mol file: 1070195-62-8.mol

Synonyms:1-(3'-amino-4'-methoxyphenyl)-1-(3'',4'',5''-trimethoxyphenyl)ethylene

Chemical Property of 1-(3'-amino-4'-methoxyphenyl)-1-(3'',4'',5''-trimethoxyphenyl)ethylene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(3'-amino-4'-methoxyphenyl)-1-(3'',4'',5''-trimethoxyphenyl)ethylene

There total 19 articles about 1-(3'-amino-4'-methoxyphenyl)-1-(3'',4'',5''-trimethoxyphenyl)ethylene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-(4'-methoxy-3'-nitrophenyl)-1-(3'',4'',5''-trimethoxyphenyl)ethylene (1070195-65-1) → 1-(3'-amino-4'-methoxyphenyl)-1-(3'',4'',5''-trimethoxyphenyl)ethylene (1070195-62-8)

Guidance literature:

With zinc; In dichloromethane; acetic acid; for 12h; Inert atmosphere;

DOI:10.1016/j.bmc.2009.07.012

Reference yield: 93.0%

1-[3'-(N-tert-butyloxycarbonylamino)-4'-methoxyphenyl]-1-(3'',4'',5''-trimethoxyphenyl)ethylene (1474060-73-5) → 1-(3'-amino-4'-methoxyphenyl)-1-(3'',4'',5''-trimethoxyphenyl)ethylene (1070195-62-8)

Guidance literature:

With hydrogenchloride; In ethanol; ethyl acetate; at 20 ℃; for 20h;

DOI:10.1055/s-0033-1339334

Reference yield: 75.0%

4-methyl-N′-(1-(3,4,5-trimethoxyphenyl)ethylidene)benzenesulfonohydrazide (1170045-84-7) + 5-bromo-2-methoxyaniline (6358-77-6) → 1-(3'-amino-4'-methoxyphenyl)-1-(3'',4'',5''-trimethoxyphenyl)ethylene (1070195-62-8)

Guidance literature:

With sodium 2'‐(dicyclohexylphosphaneyl)‐2,6‐diisopropyl‐[1,1'‐biphenyl]‐4‐sulfonate; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; potassium carbonate; In water; at 100 ℃; for 0.666667h; Sealed tube; Inert atmosphere; Microwave irradiation; Green chemistry;

DOI:10.1021/acs.orglett.9b03310

upstream raw materials:

1-(4'-methoxy-3'-nitrophenyl)-1-(3'',4'',5''-trimethoxyphenyl)ethylene

4-methyl-N′-(1-(3,4,5-trimethoxyphenyl)ethylidene)benzenesulfonohydrazide

3-amino-4-methyloxyphenyliodide

C₁₇H₁₉IO₅

Downstream raw materials:

C₃₅H₃₃NO₇

2-azido-1-methoxy-4-[1-(3,4,5-trimethoxyphenyl)vinyl]benzene

1-{2-methoxy-5-[1-(3,4,5-trimethoxyphenyl)vinyl]phenyl}-4-(3,4,5-trimethoxyphenyl)-1H-1,2,3-triazole