Technology Process of 6-iodo-2,3,4-trimethoxybenzoic acid
There total 4 articles about 6-iodo-2,3,4-trimethoxybenzoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dihydrogen peroxide; potassium hydroxide;
In
methanol;
at 65 ℃;
for 1.16667h;
DOI:10.1021/ja411146x
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: iron; ferrous(II) sulfate heptahydrate / water; ethanol / 4 h / Inert atmosphere; Reflux
2.1: sodium nitrite; hydrogenchloride; phenylphosphane / water / 0.25 h / 0 - 5 °C / Inert atmosphere
2.2: 0 - 5 °C / Inert atmosphere
3.1: dihydrogen peroxide; potassium hydroxide / methanol / 1.17 h / 65 °C
With
hydrogenchloride; ferrous(II) sulfate heptahydrate; dihydrogen peroxide; iron; phenylphosphane; potassium hydroxide; sodium nitrite;
In
methanol; ethanol; water;
DOI:10.1021/ja411146x
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium nitrite; hydrogenchloride; phenylphosphane / water / 0.25 h / 0 - 5 °C / Inert atmosphere
1.2: 0 - 5 °C / Inert atmosphere
2.1: dihydrogen peroxide; potassium hydroxide / methanol / 1.17 h / 65 °C
With
hydrogenchloride; dihydrogen peroxide; phenylphosphane; potassium hydroxide; sodium nitrite;
In
methanol; water;
DOI:10.1021/ja411146x
