2-(2-Morpholin-4-yl-benzylsulfanyl)-1-pyridin-2-yl-1,4,5,6-tetrahydro-cyclopentaimidazole

Base Information

Chemical Name:2-(2-Morpholin-4-yl-benzylsulfanyl)-1-pyridin-2-yl-1,4,5,6-tetrahydro-cyclopentaimidazole
CAS No.:117323-81-6
Molecular Formula:C₂₂H₂₄N₄OS
Molecular Weight:392.525
Hs Code.:

Synonyms:2-(2-Morpholin-4-yl-benzylsulfanyl)-1-pyridin-2-yl-1,4,5,6-tetrahydro-cyclopentaimidazole

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Chemical Property of 2-(2-Morpholin-4-yl-benzylsulfanyl)-1-pyridin-2-yl-1,4,5,6-tetrahydro-cyclopentaimidazole

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Technology Process of 2-(2-Morpholin-4-yl-benzylsulfanyl)-1-pyridin-2-yl-1,4,5,6-tetrahydro-cyclopentaimidazole

There total 5 articles about 2-(2-Morpholin-4-yl-benzylsulfanyl)-1-pyridin-2-yl-1,4,5,6-tetrahydro-cyclopentaimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 110405-99-7
2-morpholinobenzyl chloride

: 1-Pyridin-2-yl-3,4,5,6-tetrahydro-1H-cyclopentaimidazole-2-thione

: 117323-81-6
2-(2-Morpholin-4-yl-benzylsulfanyl)-1-pyridin-2-yl-1,4,5,6-tetrahydro-cyclopentaimidazole

Guidance literature:: With sodium hydroxide; In N,N-dimethyl-formamide; at 0 ℃; for 3h;
DOI:10.1021/jm950610n

Reference yield:

: 394-35-4
methyl 2-fluorobenzoate

: 117323-81-6
2-(2-Morpholin-4-yl-benzylsulfanyl)-1-pyridin-2-yl-1,4,5,6-tetrahydro-cyclopentaimidazole

Guidance literature:: Multi-step reaction with 4 steps

1: K₂CO₃ / dimethylformamide / Ambient temperature

2: LiAlH₄ / tetrahydrofuran

3: SOCl₂ / CHCl₃

4: NaOH / dimethylformamide / 3 h / 0 °C

With sodium hydroxide; lithium aluminium tetrahydride; thionyl chloride; potassium carbonate; In tetrahydrofuran; chloroform; N,N-dimethyl-formamide;
DOI:10.1021/jm950610n

Reference yield:

: 465514-33-4
(2-morpholin-4-ylphenyl)methanol

: 117323-81-6
2-(2-Morpholin-4-yl-benzylsulfanyl)-1-pyridin-2-yl-1,4,5,6-tetrahydro-cyclopentaimidazole

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / CHCl₃

2: NaOH / dimethylformamide / 3 h / 0 °C

With sodium hydroxide; thionyl chloride; In chloroform; N,N-dimethyl-formamide;
DOI:10.1021/jm950610n