isopropyl 3-(4-methoxyphenyl)propiolate

Base Information

Chemical Name:isopropyl 3-(4-methoxyphenyl)propiolate
CAS No.:157019-54-0
Molecular Formula:C₁₃H₁₄O₃
Molecular Weight:218.252
Hs Code.:

Synonyms:isopropyl 3-(4-methoxyphenyl)propiolate

Suppliers and Price of isopropyl 3-(4-methoxyphenyl)propiolate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of isopropyl 3-(4-methoxyphenyl)propiolate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of isopropyl 3-(4-methoxyphenyl)propiolate

There total 7 articles about isopropyl 3-(4-methoxyphenyl)propiolate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 108-23-6
isopropyl chloroformate

: 768-60-5
4-methoxyphenylacetylen

: 157019-54-0
isopropyl 3-(4-methoxyphenyl)propiolate

Guidance literature:: 4-methoxyphenylacetylen; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 0.5h; Schlenk technique;

isopropyl chloroformate; In tetrahydrofuran; at -78 - 20 ℃; Schlenk technique;
DOI:10.1039/c7cy02295f

Reference yield: 81.0%

: 2227-57-8
3-(4-methoxyphenyl)propynoic acid

: 67-63-0,8013-70-5
isopropyl alcohol

: 157019-54-0
isopropyl 3-(4-methoxyphenyl)propiolate

Guidance literature:: With dmap; dicyclohexyl-carbodiimide; In dichloromethane; for 12h; Ambient temperature;
DOI:10.1016/S0040-4020(01)89369-8

Reference yield:

: 51718-85-5
ethyl 3-(4-methoxyphenyl)propynoate

: 157019-54-0
isopropyl 3-(4-methoxyphenyl)propiolate

Guidance literature:: Multi-step reaction with 4 steps

1: 2.3 percent Chromat_. / quinoline, H₂ / Lindlar catalyst / hexane; various solvent(s) / 760 Torr / Ambient temperature

2: 99 percent / Br₂

3: 51 percent / KOH / aq. ethanol / 12 h / Heating

4: 81 percent / DCC, 4-dimethylaminopyridine / CH₂Cl₂ / 12 h / Ambient temperature

With quinoline; dmap; potassium hydroxide; hydrogen; bromine; dicyclohexyl-carbodiimide; Lindlar's catalyst; In ethanol; hexane; dichloromethane;
DOI:10.1016/S0040-4020(01)89369-8