Technology Process of 2,2-dimethylbut-3-en-1-yl benzoate
There total 4 articles about 2,2-dimethylbut-3-en-1-yl benzoate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Methyltriphenylphosphonium bromide;
With
potassium tert-butylate;
In
tetrahydrofuran; toluene;
for 4h;
Inert atmosphere;
2,2-dimethylhydracraldehyde benzoate;
In
tetrahydrofuran; toluene;
at -78 - 20 ℃;
Inert atmosphere;
DOI:10.1021/ol303129p
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: dmap; N-ethyl-N,N-diisopropylamine / dichloromethane / 1.5 h / 0 - 20 °C
2.1: silica gel; pyridinium chlorochromate / dichloromethane / 3 h
3.1: potassium tert-butylate / tetrahydrofuran / 4 h / 0 - 20 °C / Inert atmosphere
3.2: 1 h / -50 - 20 °C / Inert atmosphere
With
dmap; potassium tert-butylate; silica gel; N-ethyl-N,N-diisopropylamine; pyridinium chlorochromate;
In
tetrahydrofuran; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: dmap; N-ethyl-N,N-diisopropylamine / dichloromethane / 1.5 h / 0 - 20 °C
2.1: silica gel; pyridinium chlorochromate / dichloromethane / 3 h
3.1: potassium tert-butylate / tetrahydrofuran / 4 h / 0 - 20 °C / Inert atmosphere
3.2: 1 h / -50 - 20 °C / Inert atmosphere
With
dmap; potassium tert-butylate; silica gel; N-ethyl-N,N-diisopropylamine; pyridinium chlorochromate;
In
tetrahydrofuran; dichloromethane;
