α-trimethylsilyl-α-trimethylsiloxytoluene

Base Information

• Chemical Name: α-trimethylsilyl-α-trimethylsiloxytoluene
• CAS No.: 53172-92-2
• Molecular Formula: C₁₃H₂₄OSi₂
• Molecular Weight: 252.504
• Mol file: 53172-92-2.mol

Synonyms:α-trimethylsilyl-α-trimethylsiloxytoluene

Chemical Property of α-trimethylsilyl-α-trimethylsiloxytoluene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of α-trimethylsilyl-α-trimethylsiloxytoluene

There total 7 articles about α-trimethylsilyl-α-trimethylsiloxytoluene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

chloro-trimethyl-silane (75-77-4) + benzaldehyde (100-52-7) → 1,2-diphenyl-1,2-ethanediol (492-70-6,655-48-1,2325-10-2,38270-73-4,52340-78-0,579-43-1) + α-trimethylsilyl-α-trimethylsiloxytoluene (53172-92-2)

Guidance literature:

With magnesium; In N,N-dimethyl-formamide; at 20 ℃; for 4h;

DOI:10.1016/j.tet.2006.01.026

Reference yield:

chloro-trimethyl-silane (75-77-4) + benzoic acid phenyl ester (93-99-2) → (trimethylsilyl)phenylmethanol (17876-95-8) + α-trimethylsilyl-α-trimethylsiloxytoluene (53172-92-2) + benzaldehyde (100-52-7) + trimethyl(phenoxy(phenyl)methyl)silane

Guidance literature:

With tetra-n-propylammonium perchlorate; In acetonitrile; at 20 ℃; Elektroreduktion;

DOI:10.1002/prac.19933350304

Reference yield:

benzaldehyde (100-52-7) → 1,2-diphenyl-1,2-ethanediol (492-70-6,655-48-1,2325-10-2,38270-73-4,52340-78-0,579-43-1) + α-trimethylsilyl-α-trimethylsiloxytoluene (53172-92-2)

Guidance literature:

With chloro-trimethyl-silane; magnesium; In N,N-dimethyl-formamide; for 4h; Yields of byproduct given; Ambient temperature;

DOI:10.1246/cl.1995.829

upstream raw materials:

chloro-trimethyl-silane

benzyloxy-trimethylsilane

benzoic acid phenyl ester

benzaldehyde

Downstream raw materials:

1-(4-Methoxy-phenyl)-2-phenyl-2-trimethylsilanyloxy-ethanol

phenyl-2-p-tolyl-ethane-1,2-diol

1-(4-methoxyphenyl)-2-phenyl-ethane-1,2-diol

(RS)-methyl mandelate