Technology Process of C26H23NO3
There total 5 articles about C26H23NO3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
3-phenyl-1-(pyridin-2-yl)prop-2-yn-1-yl pivalate; iodobenzene;
With
bis-triphenylphosphine-palladium(II) chloride; tetra-(n-butyl)ammonium iodide; potassium carbonate; triphenylphosphine;
In
N,N-dimethyl-formamide;
Schlenk technique;
Inert atmosphere;
Glovebox;
carbon monoxide;
In
N,N-dimethyl-formamide;
at 100 ℃;
under 517.162 Torr;
Reagent/catalyst;
Solvent;
Temperature;
Pressure;
Inert atmosphere;
Schlenk technique;
DOI:10.1021/ol302947r
- Guidance literature:
-
With
tetrakis(triphenylphosphine) palladium(0); triethylamine;
In
tetrahydrofuran;
at 60 ℃;
for 20h;
Reagent/catalyst;
Solvent;
Temperature;
Inert atmosphere;
Schlenk technique;
DOI:10.1021/acs.joc.0c00161
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: ethylmagnesium bromide / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere
1.2: 3 h / -78 - 20 °C / Inert atmosphere
2.1: dmap; triethylamine / dichloromethane / 0.08 h / 0 °C
2.2: 0.67 h / 0 °C
3.1: bis-triphenylphosphine-palladium(II) chloride; triphenylphosphine; potassium carbonate; tetra-(n-butyl)ammonium iodide / N,N-dimethyl-formamide / Schlenk technique; Inert atmosphere; Glovebox
3.2: 100 °C / 517.16 Torr / Inert atmosphere; Schlenk technique
With
dmap; bis-triphenylphosphine-palladium(II) chloride; ethylmagnesium bromide; tetra-(n-butyl)ammonium iodide; potassium carbonate; triethylamine; triphenylphosphine;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ol302947r
