2-(3-bromo-phenyl)-6-chloro-4,4-dimethyl-1,2,3,4-tetrahydro-quinoline-8-carboxylic acid methyl ester

Base Information

Chemical Name:2-(3-bromo-phenyl)-6-chloro-4,4-dimethyl-1,2,3,4-tetrahydro-quinoline-8-carboxylic acid methyl ester
CAS No.:1373546-27-0
Molecular Formula:C₁₉H₁₉BrClNO₂
Molecular Weight:408.722
Hs Code.:

Synonyms:2-(3-bromo-phenyl)-6-chloro-4,4-dimethyl-1,2,3,4-tetrahydro-quinoline-8-carboxylic acid methyl ester

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Chemical Property of 2-(3-bromo-phenyl)-6-chloro-4,4-dimethyl-1,2,3,4-tetrahydro-quinoline-8-carboxylic acid methyl ester

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Technology Process of 2-(3-bromo-phenyl)-6-chloro-4,4-dimethyl-1,2,3,4-tetrahydro-quinoline-8-carboxylic acid methyl ester

There total 2 articles about 2-(3-bromo-phenyl)-6-chloro-4,4-dimethyl-1,2,3,4-tetrahydro-quinoline-8-carboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 3132-99-8
m-bromobenzoic aldehyde

: 1184597-61-2
2-aminochlorofluorobenzoic acid methyl ester

: 115-11-7,15220-85-6
isobutene

: 1373546-27-0
2-(3-bromo-phenyl)-6-chloro-4,4-dimethyl-1,2,3,4-tetrahydro-quinoline-8-carboxylic acid methyl ester

Guidance literature:: With ytterbium(III) trifluoromethanesulfonate hydrate; In acetonitrile; at 90 ℃; for 12h; sealed reaction bottle;

Reference yield: 57.0%

: 5202-89-1
4-chlorobenzenesulfonyl chloride

: 3132-99-8
m-bromobenzoic aldehyde

: 115-11-7,15220-85-6
isobutene

: 1373546-27-0
2-(3-bromo-phenyl)-6-chloro-4,4-dimethyl-1,2,3,4-tetrahydro-quinoline-8-carboxylic acid methyl ester

Guidance literature:: ytterbium(III) trifluoromethanesulfonate hydrate; In acetonitrile; at 0 - 90 ℃; for 12h; Product distribution / selectivity; Sealed tube;