1,2,3-tricyclohexylguanidine

Base Information

• Chemical Name: 1,2,3-tricyclohexylguanidine
• CAS No.: 4833-41-4
• Molecular Formula: C19H35 N3
• Molecular Weight: 305.507
• Mol file: 4833-41-4.mol

Synonyms:Guanidine,1,2,3-tricyclohexyl- (7CI,8CI); 1,2,3-Tricyclohexylguanidine;N,N',N''-Tricyclohexylguanidine; NSC 244828; Tricyclohexylguanidine

Chemical Property of 1,2,3-tricyclohexylguanidine

Chemical Property:

• Vapor Pressure: 1.28E-07mmHg at 25°C
• Boiling Point: 430.6°Cat760mmHg
• Flash Point: 214.2°C
• Density: 1.14g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,2,3-tricyclohexylguanidine

There total 15 articles about 1,2,3-tricyclohexylguanidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

cyclohexylamine (108-91-8,157973-60-9) + dicyclohexyl-carbodiimide (538-75-0) → N,N',N''-tricyclohexylguanidine (4833-41-4)

Guidance literature:

With C₂₄H₅₀N₅Si₂Y; In neat (no solvent); at 20 ℃; for 2h; Inert atmosphere; Schlenk technique;

DOI:10.1021/acs.organomet.0c00606

Reference yield: 98.0%

N',N''-dicyclohexyl-N,N-dimethylguanidine (29882-02-8) + cyclohexylamine (108-91-8,157973-60-9) → N,N',N''-tricyclohexylguanidine (4833-41-4) + dimethyl amine (124-40-3)

Guidance literature:

With [?:η¹:η⁵-(OCH2)(Me2CH2)C2B9H9]Ti(NMe2); at 110 - 115 ℃;

DOI:10.1016/j.jorganchem.2008.11.010

Reference yield: 80.0%

N-cyclohexylimidocarbonyl dichloride (2666-80-0) + cyclohexylamine (108-91-8,157973-60-9) → N,N',N''-tricyclohexylguanidine (4833-41-4)

Guidance literature:

upstream raw materials:

N-cyclohexylimidocarbonyl dichloride

cyclohexylamine

ethyl acetoacetate

dicyclohexyl-carbodiimide

Downstream raw materials:

[FeBr(C₆H₁₁N)2C(NHC₆H₁₁)]2

tin(II) bis(N,N',N''-tricyclohexylguanidinate)

Ta(N(CH₃)2)3[C₆H₁₁NC(NC₆H₁₁)NC₆H₁₁]

Nb(N(CH₃)2)3[C₆H₁₁NC(NC₆H₁₁)NC₆H₁₁]