2,3,4,5-tetramethoxybenzamide

Base Information

• Chemical Name: 2,3,4,5-tetramethoxybenzamide
• CAS No.: 109745-55-3
• Molecular Formula: C₁₁H₁₅NO₅
• Molecular Weight: 241.244
• Mol file: 109745-55-3.mol

Synonyms:2,3,4,5-tetramethoxybenzamide

Chemical Property of 2,3,4,5-tetramethoxybenzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3,4,5-tetramethoxybenzamide

There total 4 articles about 2,3,4,5-tetramethoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3,4,5-Tetramethoxybenzoylchlorid (55386-54-4) → 2,3,4,5-tetramethoxybenzamide (109745-55-3)

Guidance literature:

With ammonium hydroxide; In diethyl ether; Yield given;

DOI:10.1021/ja00252a022

Reference yield:

2-bromo-3,4,5-trimethoxybenzoic acid (23346-82-9) → 2,3,4,5-tetramethoxybenzamide (109745-55-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 90 percent / Cu powder / methanol / 18 h / Heating

2: oxalyl chloride / CH₂Cl₂ / Ambient temperature

3: 30percent NH₄OH / diethyl ether

With ammonium hydroxide; oxalyl dichloride; copper; In methanol; diethyl ether; dichloromethane;

DOI:10.1021/ja00252a022

Reference yield:

2,3,4,5-tetramethoxybenzoic acid (72023-44-0) → 2,3,4,5-tetramethoxybenzamide (109745-55-3)

Guidance literature:

Multi-step reaction with 2 steps

1: oxalyl chloride / CH₂Cl₂ / Ambient temperature

2: 30percent NH₄OH / diethyl ether

With ammonium hydroxide; oxalyl dichloride; In diethyl ether; dichloromethane;

DOI:10.1021/ja00252a022

upstream raw materials:

2,3,4,5-Tetramethoxybenzoylchlorid

2,3,4,5-tetramethoxybenzoic acid

2-bromo-3,4,5-trimethoxybenzoic acid

Eudesmic acid

Downstream raw materials:

2-{2-[6-(1-Allyloxy-ethyl)-benzo[1,3]dioxol-5-yl]-3,4,5-trimethoxy-benzyl}-malonic acid dimethyl ester

2-{2-[6-(1-Hydroxy-ethyl)-benzo[1,3]dioxol-5-yl]-3,4,5-trimethoxy-benzyl}-malonic acid dimethyl ester

5-(1-Allyloxy-ethyl)-6-(6-bromomethyl-2,3,4-trimethoxy-phenyl)-benzo[1,3]dioxole

{2-[6-(1-Allyloxy-ethyl)-benzo[1,3]dioxol-5-yl]-3,4,5-trimethoxy-phenyl}-methanol