(5R)-3-(3-fluoro-4-iodo-phenyl)-5-(4-trimethylsilanyl-[1,2,3]triazol-1-ylmethyl)-oxazolidin-2-one

Base Information

Chemical Name:(5R)-3-(3-fluoro-4-iodo-phenyl)-5-(4-trimethylsilanyl-[1,2,3]triazol-1-ylmethyl)-oxazolidin-2-one
CAS No.:916888-23-8
Molecular Formula:C₁₅H₁₈FIN₄O₂Si
Molecular Weight:460.322
Hs Code.:

Synonyms:(5R)-3-(3-fluoro-4-iodo-phenyl)-5-(4-trimethylsilanyl-[1,2,3]triazol-1-ylmethyl)-oxazolidin-2-one

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Chemical Property of (5R)-3-(3-fluoro-4-iodo-phenyl)-5-(4-trimethylsilanyl-[1,2,3]triazol-1-ylmethyl)-oxazolidin-2-one

Chemical Property:

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Technology Process of (5R)-3-(3-fluoro-4-iodo-phenyl)-5-(4-trimethylsilanyl-[1,2,3]triazol-1-ylmethyl)-oxazolidin-2-one

There total 1 articles about (5R)-3-(3-fluoro-4-iodo-phenyl)-5-(4-trimethylsilanyl-[1,2,3]triazol-1-ylmethyl)-oxazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 519003-01-1
(5R)-5-(azidomethyl)-3-(3-fluoro-4-iodophenyl)-1,3-oxazolidin-2-one

: 1066-54-2
trimethylsilylacetylene

: 916888-23-8
(5R)-3-(3-fluoro-4-iodo-phenyl)-5-(4-trimethylsilanyl-[1,2,3]triazol-1-ylmethyl)-oxazolidin-2-one

Guidance literature:: In N,N-dimethyl-formamide; at 20 - 100 ℃; for 20h;

Reference yield:

: 916888-23-8
(5R)-3-(3-fluoro-4-iodo-phenyl)-5-(4-trimethylsilanyl-[1,2,3]triazol-1-ylmethyl)-oxazolidin-2-one

: 501939-95-3
(5R)-3-(3-fluoro-4-iodophenyl)-5-(1H-1,2,3-triazol-1-ylmethyl)-1,3-oxazolidin-2-one

Guidance literature:: With tetrabutyl ammonium fluoride; acetic acid; In tetrahydrofuran; at 25 ℃; for 24h;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 916888-23-8
(5R)-3-(3-fluoro-4-iodo-phenyl)-5-(4-trimethylsilanyl-[1,2,3]triazol-1-ylmethyl)-oxazolidin-2-one

: 70978-37-9
1-(azidomethyl)-4-methoxybenzene

: 87199-17-5
4-formylphenylboronic acid,

: 2450-71-7
Propargylamine

: {2'-Fluoro-4'-[2-oxo-5-(4-trimethylsilanyl-[1,2,3]triazol-1-ylmethyl)-oxazolidin-3-yl]-biphenyl-4-ylmethyl}-[1-(4-methoxy-benzyl)-1H-[1,2,3]triazol-4-ylmethyl]-carbamic acid tert-butyl ester

: C₃₈H₄₅FN₈O₅Si

Guidance literature:: 1-(azidomethyl)-4-methoxybenzene; Propargylamine; In toluene; at 25 - 110 ℃; for 21h;

4-formylphenylboronic acid,; In 1,2-dichloro-ethane; at 25 ℃; for 0.166667h;

di-tert-butyl dicarbonate; (5R)-3-(3-fluoro-4-iodo-phenyl)-5-(4-trimethylsilanyl-[1,2,3]triazol-1-ylmethyl)-oxazolidin-2-one;