4-Ethylphenyl pyrimidine-5-carboxylate

Base Information

Chemical Name:4-Ethylphenyl pyrimidine-5-carboxylate
CAS No.:100724-16-1
Molecular Formula:C13H12 N2 O2
Molecular Weight:228.25
Hs Code.:2933599090
DSSTox Substance ID:DTXSID70695467
Wikidata:Q72498592
Mol file:100724-16-1.mol

Synonyms:DTXSID70695467;4-ethylphenyl pyrimidine-5-carboxylate

Suppliers and Price of 4-Ethylphenyl pyrimidine-5-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
ETHYL-4-PHENYL PYRIMIDINE-5-CARBOXYLATE 98.00%
5MG
$ 497.49

Total 8 raw suppliers

Chemical Property of 4-Ethylphenyl pyrimidine-5-carboxylate

Chemical Property:

Vapor Pressure:2.17E-06mmHg at 25°C
Melting Point:159-161℃
Refractive Index:1.562
Boiling Point:393.2°Cat760mmHg
Flash Point:191.6°C
PSA：52.08000
Density:1.167g/cm³
LogP:2.32030
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:228.089877630
Heavy Atom Count:17
Complexity:244

Purity/Quality:

99+% ^*data from raw suppliers

ETHYL-4-PHENYL PYRIMIDINE-5-CARBOXYLATE 98.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=CC=C(C=C1)OC(=O)C2=CN=CN=C2

Technology Process of 4-Ethylphenyl pyrimidine-5-carboxylate

There total 4 articles about 4-Ethylphenyl pyrimidine-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 33831-72-0
ethyl 3-amino-3-phenylprop-2-enoate

: 122-51-0
orthoformic acid triethyl ester

: 156647-97-1,156647-98-2,4891-69-4
6-phenylpyrimidin-4(1H)-one

: 100724-16-1
ethyl 4-phenylpyrimidine-5-carboxylate

Guidance literature:: With ammonium acetate; zinc(II) chloride; In toluene; at 100 ℃; for 48h; Inert atmosphere;
DOI:10.1021/ol900382j

Reference yield: 43.0%

: 94-02-0
ethyl 3-oxo-3-phenylpropionate

: 77287-34-4,77287-35-5,60100-09-6
formamide

: 100724-16-1
ethyl 4-phenylpyrimidine-5-carboxylate

Guidance literature:: With dipotassium peroxodisulfate; at 120 ℃; Inert atmosphere;
DOI:10.1021/acs.orglett.7b02838

Reference yield:

: 66129-60-0
ethyl-3-(dimethylamino)-2-(phenylcarbonyl)prop-2-enoate

: 6313-33-3
formamidine hydrochloride

: 100724-16-1
ethyl 4-phenylpyrimidine-5-carboxylate

Guidance literature:: formamidine hydrochloride; With sodium ethanolate; In ethanol; for 0.5h; Inert atmosphere;

ethyl-3-(dimethylamino)-2-(phenylcarbonyl)prop-2-enoate; In ethanol; Reflux;