N,N-DIMETHYL-2-PHENYL(THIOACETAMIDE)

Base Information

• Chemical Name: N,N-DIMETHYL-2-PHENYL(THIOACETAMIDE)
• CAS No.: 17709-95-4
• Molecular Formula: C10H13 N S
• Molecular Weight: 179.286
• Hs Code.: 2930909090
• Mol file: 17709-95-4.mol

Synonyms:Acetamide,N,N-dimethyl-2-phenylthio- (8CI); N,N-Dimethyl-2-phenylthioacetamide;N,N-Dimethylphenylthioacetamide; a-Phenyl-N-dimethylthioacetamide

Chemical Property of N,N-DIMETHYL-2-PHENYL(THIOACETAMIDE)

Chemical Property:

• Vapor Pressure: 0.0106mmHg at 25°C
• Melting Point: 78-80°
• Refractive Index: 1.584
• Boiling Point: 262.9°Cat760mmHg
• Flash Point: 112.8°C
• PSA: 35.33000
• Density: 1.07g/cm³
• LogP: 2.11810

Purity/Quality:

98%Min ^*data from raw suppliers

N,N-Dimethyl-2-phenylethanethioamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
• Hazard Codes: R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
• Statements: R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
• Safety Statements: S22:Do not inhale dust.; S36/37:Wear suitable protective clothing and gloves.

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N,N-DIMETHYL-2-PHENYL(THIOACETAMIDE)

There total 36 articles about N,N-DIMETHYL-2-PHENYL(THIOACETAMIDE) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-Methylselanyl-2-phenyl-ethanethione (136970-31-5) + dimethyl amine (124-40-3) → dimethyl diselenide (7101-31-7) + N,N-dimethyl-2-phenylethanethioamide (17709-95-4)

Guidance literature:

In dichloromethane;

DOI:10.1039/c39910000964

Reference yield: 90.0%

N,N-dimethyl-2-phenylacetamide (18925-69-4) → N,N-dimethyl-2-phenylethanethioamide (17709-95-4)

Guidance literature:

With Lawessons reagent; In toluene; at 100 ℃; for 4h;

DOI:10.1016/0040-4039(80)88066-X

Reference yield: 88.0%

DIMCARB (4137-10-4) + phenylacetylene (536-74-3) → N,N-dimethyl-2-phenylethanethioamide (17709-95-4)

Guidance literature:

With sulfur; Heating;

DOI:10.1055/s-1989-27197

upstream raw materials:

styrene

phenylacetaldehyde

dimethyl amine

acetophenone

Downstream raw materials:

N,N-dimethyl-2-phenylacetamide

erythro-N,N-dimethyl-2,3-diphenylthiopent-4-enamide

threo-N,N-dimethyl-2-phenyl-3-methylthiopent-4-enamide

erythro-N,N-dimethyl-2-phenyl-3-methylthiopent-4-enamide

Refernces

• 1、 Chen, Xuecheng,Han, Shiqing,Hu, Liang,Liu, Yafei,Luo, Yue,Pan, Bin,Peng, Yalan,Zhang, Jun,Zhang, Yurong. "Elemental Sulfur-Promoted Benzoxazole/Benzothiazole Formation Using a C=C Double Bond as a One-Carbon Donator". . p. 14485 - 14492. Retrieved 2021/11/12.
• 2、 Chen, Xinzhi,Ge, Xin,Jin, Hao,Qian, Chao,Zhou, Shaodong. "Transition-Metal-Free, General Construction of Thioamides from Chlorohydrocarbon, Amide and Elemental Sulfur". supporting information. p. 3403 - 3406. Retrieved 2021/06/25.